Literature DB >> 20965141

Redefining gigantomastia.

H Dafydd1, K R Roehl, L G Phillips, A Dancey, F Peart, K Shokrollahi.   

Abstract

Gigantomastia is a rare but disabling condition characterised by excessive breast growth. Most definitions of gigantomastia refer to a particular weight of excess breast tissue. We speculate that in gigantomastia the weight of the breasts contributes significantly to the BMI, which has implications for healthcare rationing. This study aims to establish the contribution breast tissue makes to BMI in gigantomastia. In so doing, we propose a new definition of gigantomastia. Retrospective data was collected from the case notes of 68 females who underwent breast reduction or therapeutic mastectomy for gigantomastia. For the purposes of patient inclusion, gigantomastia is arbitrarily defined as excessive breast growth of over 1.5kg per breast. The difference between pre- and post-operative BMI is statistically significant (P<0.001). Mean pre-operative BMI is 38.7 with a mean specimen weight of 4506g. Mean contribution of specimen to body weight is 4.29%. There is no correlation between pre-operative body weight and the percentage contribution the breast resection specimen makes to body weight. Based on our data, we define gigantomastia as excess breast tissue that contributes 3% or more to the patient's total body weight, approximately one standard deviation below the mean. We suggest that the estimated excess breast tissue weight is taken into account when calculating pre-operative BMI in the gigantomastia population. The challenge of estimating excess breast weight pre-operatively may be met by 3D photography coupled with computer-assisted volumetry. Copyright Â
© 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

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Mesh:

Year:  2010        PMID: 20965141     DOI: 10.1016/j.bjps.2010.04.043

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  13 in total

1.  Gestational gigantomastia with spontaneous resolution in an Indian woman.

Authors:  Tejas Venkataram; Sumanth Raghuprakash
Journal:  BMJ Case Rep       Date:  2018-03-28

2.  Bilateral axillary masses mimicking as accessory breast with multiple fibroadenoma and bilateral gigantomastia in HIV-positive patient.

Authors:  Saumya Singh; Anand K Mishra; S Tewari; Sanjeev Kumar
Journal:  BMJ Case Rep       Date:  2013-06-24

3.  Idiopathic gigantomastia: newer mechanistic insights implicating the paracrine milieu.

Authors:  Liza Das; Ashutosh Rai; Kim Vaiphei; Akhil Garg; Subair Mohsina; Anil Bhansali; Pinaki Dutta; Satyaswarup Tripathy
Journal:  Endocrine       Date:  2019-09-09       Impact factor: 3.633

4.  Utilization of Inferiorly Based Dermofat Flap in Breast Reconstruction after Simple Mastectomy due to Gigantomastia.

Authors:  A Bogdanov-Berezovsky; Y Krieger; Y Shoham; E Silberstein
Journal:  Case Rep Surg       Date:  2013-12-05

5.  Gestational Gigantomastia Complicating Pregnancy: A Case Report and Review of the Literature.

Authors:  Shadi Rezai; Jenna T Nakagawa; John Tedesco; Annika Chadee; Sri Gottimukkala; Ray Mercado; Cassandra E Henderson
Journal:  Case Rep Obstet Gynecol       Date:  2015-12-02

6.  Risk Factors for Complications after Reduction Mammoplasty: A Meta-Analysis.

Authors:  Min-Xia Zhang; Chun-Ye Chen; Qing-Qing Fang; Ji-Hua Xu; Xiao-Feng Wang; Bang-Hui Shi; Li-Hong Wu; Wei-Qiang Tan
Journal:  PLoS One       Date:  2016-12-09       Impact factor: 3.240

7.  Severe Gestational Gigantomastia: from Mastectomy to Staged Autologous Breast Reconstruction. A Case Report.

Authors:  Noureddine Hassayoune; Mina Mhallem Gziri; Audrey Lentini; Theodoros Chrelias; Jennifer Hammer; Martine Berlière; Benoît Lengelé; Maude Coyette
Journal:  JPRAS Open       Date:  2021-05-18

8.  Pseudoangiomatous Stromal Hyperplasia: A Rare Cause of Idiopathic Gigantomastia.

Authors:  Mélissa Roy; James Lee; Salah Aldekhayel; Tassos Dionisopoulos
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-09-04

9.  Reduction mammoplasty operative techniques for improved outcomes in the treatment of gigantomastia.

Authors:  Brent R Degeorge; David L Colen; Alexander F Mericli; David B Drake
Journal:  Eplasty       Date:  2013-10-18

10.  Stromal-epithelial cell interactions and alteration of branching morphogenesis in macromastic mammary glands.

Authors:  Aimei Zhong; Guohua Wang; Jie Yang; Qijun Xu; Quan Yuan; Yanqing Yang; Yun Xia; Ke Guo; Raymund E Horch; Jiaming Sun
Journal:  J Cell Mol Med       Date:  2014-04-10       Impact factor: 5.310

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