Literature DB >> 20964210

Effect of longitudinal magnetic fields on a simulated in-line 6 MV linac.

J St Aubin1, D M Santos, S Steciw, B G Fallone.   

Abstract

PURPOSE: Linac-magnetic resonance (MR) systems have been proposed in order to achieve realtime image guided radiotherapy. The design of a new linac-MR system with the in-line 6 MV linac generating x-rays along the symmetry axis of an open MR imager is outlined. This new design allows for a greater MR field strength to achieve better quality images while reducing hot and cold spots in treatment planning. An investigation of linac's performance in the longitudinal fringe magnetic fields of the MR imager is given.
METHODS: The open MR imager fringe magnetic field was modeled using the analytic solution of the magnetic field generated from current carrying loops. The derived solution was matched to the magnetic fringe field isolines provided for a 0.5 T open MR imager through Monte Carlo optimization. The optimized field solution was then added to the previously validated 6 MV linac simulation to quantify linac's performance in the fringe magnetic field of a 0.5 T MR imager. To further the investigation, linac's performance in large fringe fields expected from other imagers was investigated through the addition of homogeneous longitudinal fields.
RESULTS: The Monte Carlo optimization of the analytic current loop solution provided good agreement with the magnetic fringe field isolines supplied by the manufacturer. The range of magnetic fields the linac is expected to experience when coupled to the 0.5 T MR imager was determined to be from 0.0022 to 0.011 T (as calculated at the electron gun cathode). The effect of the longitudinal magnetic field on the electron beam was observed to be only in the electron gun. The longitudinal field changed the electron gun optics, affecting beam characteristics, such as a slight increase in the injection current and beam diameter, and an increasingly nonlaminar transverse phase space. Although the target phase space showed little change in its energy spectrum from the altered injection phase space, a reduction in the target current and spatial distribution peak intensity was observed. Despite these changes, the target phase space had little effect on the depth dose curves or dose profiles calculated for a 40 x 40 cm2 field at 1.5 cm depth. At longitudinal fields larger than 0.012 T, a drastic reduction in the injection current from the electron gun was observed due to a large fraction of electrons striking the anode. This further reduced the target current, which reached a minimum of 28 +/- 2 mA at 0.06 T. A slow increase in the injection and target currents was observed at fields larger than 0.06 T due to greater beam collimation in the anode beam tube.
CONCLUSIONS: In an effort to achieve higher quality images and a reduction in hot and cold spots in the treatment plan, a parallel configuration linac-MR system is presented. The longitudinal magnetic fields of the MR imager caused large beam losses within the electron gun. These losses may be eliminated through a redesign of the electron gun optics incorporating a longitudinal magnetic field, or through magnetic shielding, which has already been proven successful for the transverse configuration.

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Year:  2010        PMID: 20964210     DOI: 10.1118/1.3481513

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  7 in total

1.  A study of the effect of in-line and perpendicular magnetic fields on beam characteristics of electron guns in medical linear accelerators.

Authors:  Dragoş E Constantin; Rebecca Fahrig; Paul J Keall
Journal:  Med Phys       Date:  2011-07       Impact factor: 4.071

Review 2.  MR-guided radiation therapy: transformative technology and its role in the central nervous system.

Authors:  Yue Cao; Chia-Lin Tseng; James M Balter; Feifei Teng; Hemant A Parmar; Arjun Sahgal
Journal:  Neuro Oncol       Date:  2017-04-01       Impact factor: 12.300

3.  Performance of a clinical gridded electron gun in magnetic fields: Implications for MRI-linac therapy.

Authors:  Brendan Whelan; Lois Holloway; Dragos Constantin; Brad Oborn; Magdalena Bazalova-Carter; Rebecca Fahrig; Paul Keall
Journal:  Med Phys       Date:  2016-11       Impact factor: 4.071

4.  A novel electron gun for inline MRI-linac configurations.

Authors:  Dragoş E Constantin; Lois Holloway; Paul J Keall; Rebecca Fahrig
Journal:  Med Phys       Date:  2014-02       Impact factor: 4.071

5.  A novel electron accelerator for MRI-Linac radiotherapy.

Authors:  Brendan Whelan; Stephen Gierman; Lois Holloway; John Schmerge; Paul Keall; Rebecca Fahrig
Journal:  Med Phys       Date:  2016-03       Impact factor: 4.071

6.  Achieving High Current Stability of Gated Carbon Nanotube Cold Cathode Electron Source Using IGBT Modulation for X-ray Source Application.

Authors:  Yajie Guo; Junfan Wang; Baohong Li; Yu Zhang; Shaozhi Deng; Jun Chen
Journal:  Nanomaterials (Basel)       Date:  2022-05-31       Impact factor: 5.719

Review 7.  Imaging of GBM in the Age of Molecular Markers and MRI Guided Adaptive Radiation Therapy.

Authors:  Salah Dajani; Virginia B Hill; John A Kalapurakal; Craig M Horbinski; Eric G Nesbit; Sean Sachdev; Amulya Yalamanchili; Tarita O Thomas
Journal:  J Clin Med       Date:  2022-10-10       Impact factor: 4.964

  7 in total

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