Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cyclophilin A: promising new target in cardiovascular therapy.

Literature DB >> 20962430

Cyclophilin A: promising new target in cardiovascular therapy.

Kimio Satoh¹, Hiroaki Shimokawa, Bradford C Berk.

Abstract

Cyclophilin A (CyPA) has been studied as a multifunctional protein that is upregulated in a variety of inflammatory conditions, such as rheumatoid arthritis, autoimmune disease, and cancer. CyPA has been classified as an immunophilin and has a variety of intracellular functions, including intracellular signaling, protein trafficking, and the regulation of other proteins activity. Besides its intracellular functions, CyPA is a secreted molecule that has a physiological and pathological role in cardiovascular diseases, making it a potential biomarker and mediator in cardiovascular diseases, such as vascular stenosis, atherosclerosis, and abdominal aortic aneurysms.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2010 PMID： 20962430 PMCID： PMC3052698 DOI： 10.1253/circj.cj-10-0904

Source DB: PubMed Journal: Circ J ISSN： 1346-9843 Impact factor: 2.993

101 in total

Review 1. Role of oxidative stress in cardiac hypertrophy and remodeling.

Authors: Eiki Takimoto; David A Kass
Journal: Hypertension Date: 2006-12-26 Impact factor: 10.190

2. Circulating smooth muscle progenitor cells: novel players in plaque stability.

Authors: Kimio Satoh; Bradford C Berk
Journal: Cardiovasc Res Date: 2007-12-04 Impact factor: 10.787

3. Bone marrow transplantation reveals that recipient AT1a receptors are required to initiate angiotensin II-induced atherosclerosis and aneurysms.

Authors: Lisa A Cassis; Debra L Rateri; Hong Lu; Alan Daugherty
Journal: Arterioscler Thromb Vasc Biol Date: 2006-12-07 Impact factor: 8.311

4. Important role of erythropoietin receptor to promote VEGF expression and angiogenesis in peripheral ischemia in mice.

Authors: Makoto Nakano; Kimio Satoh; Yoshihiro Fukumoto; Yoshitaka Ito; Yutaka Kagaya; Naoto Ishii; Kazuo Sugamura; Hiroaki Shimokawa
Journal: Circ Res Date: 2007-02-09 Impact factor: 17.367

5. Cyclophilin A differentially activates monocytes and endothelial cells: role of purity, activity, and endotoxin contamination in commercial preparations.

Authors: Sravan K Payeli; Cordelia Schiene-Fischer; Jan Steffel; Giovanni G Camici; Izabela Rozenberg; Thomas F Lüscher; Felix C Tanner
Journal: Atherosclerosis Date: 2007-10-24 Impact factor: 5.162

6. NOX1 deficiency protects from aortic dissection in response to angiotensin II.

Authors: Gaetan Gavazzi; Christine Deffert; Candice Trocme; Michela Schäppi; François R Herrmann; Karl-Heinz Krause
Journal: Hypertension Date: 2007-05-14 Impact factor: 10.190

7. Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice.

Authors: Jiusong Sun; Galina K Sukhova; Min Yang; Paul J Wolters; Lindsey A MacFarlane; Peter Libby; Chongxiu Sun; Yadong Zhang; Jian Liu; Terri L Ennis; Rebecca Knispel; Wanfen Xiong; Robert W Thompson; B Timothy Baxter; Guo-Ping Shi
Journal: J Clin Invest Date: 2007-11 Impact factor: 14.808

8. Cyclophilin A produced by thymocytes regulates the migration of murine bone marrow cells.

Authors: Ludmila M Khromykh; Natalia L Kulikova; Tatiana V Anfalova; Tatiana A Muranova; Vyacheslav M Abramov; Anatoliy M Vasiliev; Valentin S Khlebnikov; Dmitriy B Kazansky
Journal: Cell Immunol Date: 2007-12-20 Impact factor: 4.868

9. Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A.

Authors: Jesse M Damsker; Michael I Bukrinsky; Stephanie L Constant
Journal: J Leukoc Biol Date: 2007-05-31 Impact factor: 4.962

10. Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.

Authors: Changlian Zhu; Xiaoyang Wang; Johanna Deinum; Zhiheng Huang; Jianfeng Gao; Nazanine Modjtahedi; Martha R Neagu; Michael Nilsson; Peter S Eriksson; Henrik Hagberg; Jeremy Luban; Guido Kroemer; Klas Blomgren
Journal: J Exp Med Date: 2007-07-16 Impact factor: 14.307

30 in total

1. Alzheimer's disease: A breach in the blood-brain barrier.

Authors: Peter Carmeliet; Bart De Strooper
Journal: Nature Date: 2012-05-23 Impact factor: 49.962

2. Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine.

Authors: Michelle A Erickson; Kim Hansen; William A Banks
Journal: Brain Behav Immun Date: 2012-07-15 Impact factor: 7.217

3. Molecular cloning, expression, and characterization of cyclophilin A from Clonorchis sinensis.

Authors: Weihua Wu; Jiajia Chen; Suxiang Zeng; Zhaoping Zhang; Wenjia Gan; Xinbing Yu; Xuchu Hu
Journal: Parasitol Res Date: 2011-03-01 Impact factor: 2.289

4. Imbalanced Production of Reactive Oxygen Species and Mitochondrial Antioxidant SOD2 in Fabry Disease-Specific Human Induced Pluripotent Stem Cell-Differentiated Vascular Endothelial Cells.

Authors: Wei-Lien Tseng; Shih-Jie Chou; Huai-Chih Chiang; Mong-Lien Wang; Chian-Shiu Chien; Kuan-Hsuan Chen; Hsin-Bang Leu; Chien-Ying Wang; Yuh-Lih Chang; Yung-Yang Liu; Yuh-Jyh Jong; Shinn-Zong Lin; Shih-Hwa Chiou; Shing-Jong Lin; Wen-Chung Yu
Journal: Cell Transplant Date: 2016-12-06 Impact factor: 4.064

5. Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A.

Authors: Maysam Takapoo; Ali H Chamseddine; Ramesh C Bhalla; Francis J Miller
Journal: Vascul Pharmacol Date: 2011-07-12 Impact factor: 5.773

6. Determination of the Full Catalytic Cycle among Multiple Cyclophilin Family Members and Limitations on the Application of CPMG-RD in Reversible Catalytic Systems.

Authors: Michael J Holliday; Geoffrey S Armstrong; Elan Z Eisenmesser
Journal: Biochemistry Date: 2015-09-11 Impact factor: 3.162

7. Dietary vitamin D deficiency in rats from middle to old age leads to elevated tyrosine nitration and proteomics changes in levels of key proteins in brain: implications for low vitamin D-dependent age-related cognitive decline.

Authors: Jeriel T R Keeney; Sarah Förster; Rukhsana Sultana; Lawrence D Brewer; Caitlin S Latimer; Jian Cai; Jon B Klein; Nada M Porter; D Allan Butterfield
Journal: Free Radic Biol Med Date: 2013-07-18 Impact factor: 7.376

8. Salivary gland proteome of the human malaria vector, Anopheles campestris-like (Diptera: Culicidae).

Authors: Sriwatapron Sor-Suwan; Narissara Jariyapan; Sittiruk Roytrakul; Atchara Paemanee; Atiporn Saeung; Sorawat Thongsahuan; Benjarat Phattanawiboon; Paul A Bates; Yong Poovorawan; Wej Choochote
Journal: Parasitol Res Date: 2012-12-22 Impact factor: 2.289

9. Functions of cyclophilin A in atherosclerosis.

Authors: Zhang Tian-Tian; Zhang Jun-Feng; Ge Heng
Journal: Exp Clin Cardiol Date: 2013

10. Cyclophilin 19 secreted in the host cell cytosol by Trypanosoma cruzi promotes ROS production required for parasite growth.

Authors: Gregory Pedroso Dos Santos; Fernanda Midori Abukawa; Normanda Souza-Melo; Laura Maria Alcântara; Paula Bittencourt-Cunha; Carolina Borsoi Moraes; Bijay Kumar Jha; Bradford S McGwire; Nilmar Silvio Moretti; Sergio Schenkman
Journal: Cell Microbiol Date: 2020-12-09 Impact factor: 3.715