Literature DB >> 20961102

Biocompatibility of calcined mesoporous silica particles with cellular bioenergetics in murine tissues.

Mariam Al Shamsi1, Mohammed T Al Samri, Suhail Al-Salam, Walter Conca, Sami Shaban, Sheela Benedict, Saeed Tariq, Ankush V Biradar, Harvey S Penefsky, Tewodros Asefa, Abdul-Kader Souid.   

Abstract

A novel in vitro system was developed to investigate the effects of two forms of calcined mesoporous silica particles (MCM41-cal and SBA15-cal) on cellular respiration of mouse tissues. O(2) consumption by lung, liver, kidney, spleen, and pancreatic tissues was unaffected by exposure to 200 μg/mL MCM41-cal or SBA15-cal for several hours. Normal tissue histology was confirmed by light microscopy. Intracellular accumulation of the particles in the studied tissues was evident by electron microscopy. The results show reasonable in vitro biocompatibility of the mesoporous silicas with murine tissue bioenergetics.

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Year:  2010        PMID： 20961102     DOI： 10.1021/tx100245j

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN： 0893-228X            Impact factor:   3.739


  10 in total

Review 1.  The practicality of mesoporous silica nanoparticles as drug delivery devices and progress toward this goal.

Authors:  Robert Roggers; Shrey Kanvinde; Suthida Boonsith; David Oupický
Journal:  AAPS PharmSciTech       Date:  2014-05-29       Impact factor: 3.246

2.  Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica nanoparticles in a murine xenograft tumor model.

Authors:  Huan Meng; Min Xue; Tian Xia; Zhaoxia Ji; Derrick Y Tarn; Jeffrey I Zink; Andre E Nel
Journal:  ACS Nano       Date:  2011-04-27       Impact factor: 15.881

3.  Derangements of liver tissue bioenergetics in concanavalin A-induced hepatitis.

Authors:  Mariam Al-Shamsi; Allen Shahin; Eric P K Mensah-Brown; Abdul-Kader Souid
Journal:  BMC Gastroenterol       Date:  2013-01-12       Impact factor: 3.067

4.  Lung toxicities of core-shell nanoparticles composed of carbon, cobalt, and silica.

Authors:  Mohammed T Al Samri; Rafael Silva; Saeeda Almarzooqi; Alia Albawardi; Aws Rashad Diab Othman; Ruqayya S M S Al Hanjeri; Shaikha Km Al Dawaar; Saeed Tariq; Abdul-Kader Souid; Tewodros Asefa
Journal:  Int J Nanomedicine       Date:  2013-03-21

5.  Bioenergetics of the spinal cord in experimental autoimmune encephalitis of rats.

Authors:  Mariam Al-Shamsi; Allen Shahin; Marwa F Ibrahim; Saeed Tareq; Abdul-Kader Souid; Eric P K Mensah-Brown
Journal:  BMC Neurosci       Date:  2015-06-20       Impact factor: 3.288

6.  In vitro biocompatibility of calcined mesoporous silica particles and fetal blood cells.

Authors:  Mohammed T Al Samri; Ankush V Biradar; Ahmed R Alsuwaidi; Ghazala Balhaj; Suleiman Al-Hammadi; Safa Shehab; Suhail Al-Salam; Saeed Tariq; Thachillath Pramathan; Sheela Benedict; Tewodros Asefa; Abdul-Kader Souid
Journal:  Int J Nanomedicine       Date:  2012-08-03

7.  Lung tissue bioenergetics and caspase activity in rodents.

Authors:  Ahmed R Alsuwaidi; Mohammed T Alsamri; Ali S Alfazari; Saeeda Almarzooqi; Alia Albawardi; Aws R Othman; Thachillath Pramathan; Stacey M Hartwig; Steven M Varga; Abdul-Kader Souid
Journal:  BMC Res Notes       Date:  2013-01-12

8.  A preparation of murine liver fragments for in vitro studies: liver preparation for toxicological studies.

Authors:  Ali S Alfazari; Bayan Al-Dabbagh; Saeeda Almarzooqi; Alia Albawardi; Abdul-Kader Souid
Journal:  BMC Res Notes       Date:  2013-02-25

9.  Bioenergetics of murine lungs infected with respiratory syncytial virus.

Authors:  Ahmed R Alsuwaidi; Sheela Benedict; Jose Kochiyil; Farah Mustafa; Stacey M Hartwig; Saeeda Almarzooqi; Alia Albawardi; Tahir A Rizvi; Steven M Varga; Abdul-Kader Souid
Journal:  Virol J       Date:  2013-01-15       Impact factor: 4.099

10.  Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin.

Authors:  Ali S Alfazari; Bayan Al-Dabbagh; Saeeda Almarzooqi; Alia Albawardi; Abdul-Kader Souid
Journal:  BMC Pharmacol Toxicol       Date:  2013-02-28       Impact factor: 2.483
  10 in total

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