PURPOSE: To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging. METHODS: The study included 32 patients presenting with proptosis. Every patient was subjected to a clinical examination; conventional MRI "T1 weighted, T2 weighted, and post-contrast T1 weighted if needed;" diffusion-weighted MRI; and proton magnetic resonance spectroscopy. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed. RESULTS: Diffusion-weighted MRI can be used to differentiate between benign lesions and malignant tumors in 75% of cases; however, overlap occurred in 25% of cases with benign tumors showing restricted diffusion while proton magnetic resonance spectroscopy could differentiate between benign and malignant tumors in 93.7% of cases. CONCLUSION: Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.
PURPOSE: To evaluate the role of diffusion-weighted magnetic resonance imaging and proton magnetic resonance spectroscopy in diagnosis of different orbital masses and their advantages over conventional magnetic resonance imaging. METHODS: The study included 32 patients presenting with proptosis. Every patient was subjected to a clinical examination; conventional MRI "T1 weighted, T2 weighted, and post-contrast T1 weighted if needed;" diffusion-weighted MRI; and proton magnetic resonance spectroscopy. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed. RESULTS: Diffusion-weighted MRI can be used to differentiate between benign lesions and malignant tumors in 75% of cases; however, overlap occurred in 25% of cases with benign tumors showing restricted diffusion while proton magnetic resonance spectroscopy could differentiate between benign and malignant tumors in 93.7% of cases. CONCLUSION: Diffusion-weighted MRI and proton magnetic resonance spectroscopy increased the accuracy of diagnosis of orbital masses through giving in vivo tissue characterization; with magnetic resonance spectroscopy being more accurate.
Authors: K Haradome; H Haradome; Y Usui; S Ueda; T C Kwee; K Saito; K Tokuuye; J Matsubayashi; T Nagao; H Goto Journal: AJNR Am J Neuroradiol Date: 2014-05-29 Impact factor: 3.825