Literature DB >> 20955923

Healing genes in the nervous system.

Xandra O Breakefield1, Miguel Sena-Esteves.   

Abstract

The evolution of gene therapy has led to the development of promising new therapeutic approaches. This NeuroView will introduce the variety of delivery vehicles currently available for gene therapy, a range of preclinical strategies for tackling major diseases of the nervous system, the clinical limitations, and ethical considerations.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20955923      PMCID: PMC3076203          DOI: 10.1016/j.neuron.2010.10.005

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  16 in total

Review 1.  Gene therapy for Parkinson's disease.

Authors:  Tomas Bjorklund; Jeffrey H Kordower
Journal:  Mov Disord       Date:  2010       Impact factor: 10.338

Review 2.  Hematopoietic stem cell transplantation and hematopoietic stem cell gene therapy in X-linked adrenoleukodystrophy.

Authors:  Nathalie Cartier; Patrick Aubourg
Journal:  Brain Pathol       Date:  2010-07       Impact factor: 6.508

3.  Silencing Nogo-A promotes functional recovery in demyelinating disease.

Authors:  Yuhong Yang; Yue Liu; Ping Wei; Haiyan Peng; Ryan Winger; Rehana Z Hussain; Li-Hong Ben; Petra D Cravens; Anne R Gocke; Krishna Puttaparthi; Michael K Racke; Dana M McTigue; Amy E Lovett-Racke
Journal:  Ann Neurol       Date:  2010-04       Impact factor: 10.422

4.  Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice.

Authors:  Deborah A Ryan; Michael A Mastrangelo; Wade C Narrow; Mark A Sullivan; Howard J Federoff; William J Bowers
Journal:  Mol Ther       Date:  2010-06-15       Impact factor: 11.454

5.  Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice.

Authors:  Lori Lebson; Kevin Nash; Siddharth Kamath; Donna Herber; Nikisha Carty; Daniel C Lee; Qingyou Li; Karoly Szekeres; Umesh Jinwal; John Koren; Chad A Dickey; Paul E Gottschall; Dave Morgan; Marcia N Gordon
Journal:  J Neurosci       Date:  2010-07-21       Impact factor: 6.167

6.  Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF.

Authors:  Adrian P Kells; Jamie Eberling; Xiaomin Su; Philip Pivirotto; John Bringas; Piotr Hadaczek; Wade C Narrow; William J Bowers; Howard J Federoff; John Forsayeth; Krystof S Bankiewicz
Journal:  J Neurosci       Date:  2010-07-14       Impact factor: 6.167

Review 7.  "Buy one get one free": armed viruses for the treatment of cancer cells and their microenvironment.

Authors:  Balveen Kaur; Timothy P Cripe; E Antonio Chiocca
Journal:  Curr Gene Ther       Date:  2009-10       Impact factor: 4.391

Review 8.  Viral vectors and delivery strategies for CNS gene therapy.

Authors:  Steven J Gray; Kenton T Woodard; R Jude Samulski
Journal:  Ther Deliv       Date:  2010-10

9.  Intraventricular brain injection of adeno-associated virus type 1 (AAV1) in neonatal mice results in complementary patterns of neuronal transduction to AAV2 and total long-term correction of storage lesions in the brains of beta-glucuronidase-deficient mice.

Authors:  Marco A Passini; Deborah J Watson; Charles H Vite; Daniel J Landsburg; Alyson L Feigenbaum; John H Wolfe
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

10.  Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.

Authors:  Eloise Hudry; Debby Van Dam; Wim Kulik; Peter P De Deyn; Femke S Stet; Ornella Ahouansou; Abdellatif Benraiss; André Delacourte; Pierre Bougnères; Patrick Aubourg; Nathalie Cartier
Journal:  Mol Ther       Date:  2009-08-04       Impact factor: 11.454

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  2 in total

Review 1.  Viral vectors for therapy of neurologic diseases.

Authors:  Sourav R Choudhury; Eloise Hudry; Casey A Maguire; Miguel Sena-Esteves; Xandra O Breakefield; Paola Grandi
Journal:  Neuropharmacology       Date:  2016-02-21       Impact factor: 5.250

2.  ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model.

Authors:  Anthony Donsante; Ling Yi; Patricia M Zerfas; Lauren R Brinster; Patricia Sullivan; David S Goldstein; Joseph Prohaska; Jose A Centeno; Elisabeth Rushing; Stephen G Kaler
Journal:  Mol Ther       Date:  2011-08-30       Impact factor: 11.454

  2 in total

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