Literature DB >> 2095375

Antitumor agents, 115. Seselidiol, a new cytotoxic polyacetylene from Seseli mairei.

C Q Hu1, J J Chang, K H Lee.   

Abstract

Seselidiol [1], a new polyacetylene, has been isolated from the roots of Seseli mairei. On the basis of chemical and spectroscopic evidence, its structure has been established as heptadeca-1,8(Z)-diene-4,6-diyne-3,10-diol. Seselidiol and its acetate have been demonstrated to show moderate cytotoxicity against KB, P-388, and L-1210 tumor cells.

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Year:  1990        PMID: 2095375     DOI: 10.1021/np50070a022

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  3 in total

Review 1.  Anticancer activity of natural and synthetic acetylenic lipids.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2006-10       Impact factor: 1.880

2.  Evaluation of the Antioxidant Potency of Seseli L. Species (Apiaceae).

Authors:  Alev Önder; Ahsen Sevde Çinar; Sezen Yilmaz Sarialtin; Mehmet Necat Izgi; Tülay Çoban
Journal:  Turk J Pharm Sci       Date:  2020-04-24

Review 3.  Bioactive C17 and C18 Acetylenic Oxylipins from Terrestrial Plants as Potential Lead Compounds for Anticancer Drug Development.

Authors:  Lars Porskjær Christensen
Journal:  Molecules       Date:  2020-05-31       Impact factor: 4.411

  3 in total

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