Literature DB >> 20953582

The beta and alpha cell-specific Znt8-knockout mouse model: new mechanistic insights?

M El Muayed, W L Lowe.   

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Year:  2010        PMID： 20953582     DOI： 10.1007/s00125-010-1934-2

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  8 in total

1.  Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.

Authors:  Malek El Muayed; Liana K Billings; Meera R Raja; Xiaomin Zhang; Paul J Park; Marsha V Newman; Dixon B Kaufman; Thomas V O'Halloran; William L Lowe
Journal:  J Endocrinol       Date:  2010-05-27       Impact factor: 4.286

Review 2.  Think zinc: New roles for zinc in the control of insulin secretion.

Authors:  Guy A Rutter
Journal:  Islets       Date:  2010 Jan-Feb       Impact factor: 2.694

3.  Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.

Authors:  Taiho Kambe; Hiroshi Narita; Yuko Yamaguchi-Iwai; Junko Hirose; Tatsuaki Amano; Naomi Sugiura; Ryuzo Sasaki; Koshi Mori; Toshihiko Iwanaga; Masaya Nagao
Journal:  J Biol Chem       Date:  2002-03-19       Impact factor: 5.157

4.  Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

Authors:  N Wijesekara; F F Dai; A B Hardy; P R Giglou; A Bhattacharjee; V Koshkin; F Chimienti; H Y Gaisano; G A Rutter; M B Wheeler
Journal:  Diabetologia       Date:  2010-04-28       Impact factor: 10.122

5.  Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

Authors:  K Lemaire; M A Ravier; A Schraenen; J W M Creemers; R Van de Plas; M Granvik; L Van Lommel; E Waelkens; F Chimienti; G A Rutter; P Gilon; P A in't Veld; F C Schuit
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-18       Impact factor: 11.205

6.  Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands.

Authors:  C Murgia; C Devirgiliis; E Mancini; G Donadel; P Zalewski; G Perozzi
Journal:  Nutr Metab Cardiovasc Dis       Date:  2008-12-17       Impact factor: 4.222

7.  Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility.

Authors:  X F Huang; P Arvan
Journal:  J Biol Chem       Date:  1995-09-01       Impact factor: 5.157

8.  Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Authors:  Tamara J Nicolson; Elisa A Bellomo; Nadeeja Wijesekara; Merewyn K Loder; Jocelyn M Baldwin; Armen V Gyulkhandanyan; Vasilij Koshkin; Andrei I Tarasov; Raffaella Carzaniga; Katrin Kronenberger; Tarvinder K Taneja; Gabriela da Silva Xavier; Sarah Libert; Philippe Froguel; Raphael Scharfmann; Volodymir Stetsyuk; Philippe Ravassard; Helen Parker; Fiona M Gribble; Frank Reimann; Robert Sladek; Stephen J Hughes; Paul R V Johnson; Myriam Masseboeuf; Remy Burcelin; Stephen A Baldwin; Ming Liu; Roberto Lara-Lemus; Peter Arvan; Frans C Schuit; Michael B Wheeler; Fabrice Chimienti; Guy A Rutter
Journal:  Diabetes       Date:  2009-06-19       Impact factor: 9.461
  8 in total

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