Hong Pan1, Bo Chen, Lian-Fu Deng. 1. Department of Orthopaedics, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Abstract
OBJECTIVE: To evaluate the effect of the stabilization of the Coflex device on the biomechanical behavior of the instrumented and adjacent spinal segments. METHODS: The study was carried out at the Department of Orthopedics, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, Shanghai, China between September 2009 and May 2010. Upon validation, a finite element model of L3-S1 segment was developed to simulate and analyze the biomechanics of the intact and Coflex implanted states subjected to simulate loading of flexion, extension, lateral bending, and axial rotation. RESULTS: This study predicted that the segmental motion, intradiscal pressure, and facet contact force at the levels adjacent to the Coflex implanted level were not significantly affected by the implantation of Coflex device. There was a significant decrease in range of motion in extension at the instrumented level of the Coflex implanted model relative to the intact model. Furthermore, the level implanted with Coflex device showed a significant decrease in intradiscal pressure in extension and a decrease in facet contact force in extended, lateral bending and axial rotational conditions, compared with the intact model. CONCLUSION: This study suggests that the Coflex device has the potential of effectively unloading the disc in extension and the facet joints in extension, lateral bending, and axial rotation at the Coflex implanted level, without deleterious effects on the adjacent segments under the simulated physiological condition.
OBJECTIVE: To evaluate the effect of the stabilization of the Coflex device on the biomechanical behavior of the instrumented and adjacent spinal segments. METHODS: The study was carried out at the Department of Orthopedics, Shanghai Institute of Traumatology and Orthopedics, Ruijin Hospital, Shanghai, China between September 2009 and May 2010. Upon validation, a finite element model of L3-S1 segment was developed to simulate and analyze the biomechanics of the intact and Coflex implanted states subjected to simulate loading of flexion, extension, lateral bending, and axial rotation. RESULTS: This study predicted that the segmental motion, intradiscal pressure, and facet contact force at the levels adjacent to the Coflex implanted level were not significantly affected by the implantation of Coflex device. There was a significant decrease in range of motion in extension at the instrumented level of the Coflex implanted model relative to the intact model. Furthermore, the level implanted with Coflex device showed a significant decrease in intradiscal pressure in extension and a decrease in facet contact force in extended, lateral bending and axial rotational conditions, compared with the intact model. CONCLUSION: This study suggests that the Coflex device has the potential of effectively unloading the disc in extension and the facet joints in extension, lateral bending, and axial rotation at the Coflex implanted level, without deleterious effects on the adjacent segments under the simulated physiological condition.
Authors: Zhiyuan Guo; Guangfei Liu; Lu Wang; Yuejiang Zhao; Ye Zhao; Shouliang Lu; Cai Cheng Journal: Am J Transl Res Date: 2022-07-15 Impact factor: 3.940