Literature DB >> 20953319

Solubility of α-Tocopheryl Succinate in Supercritical Carbon Dioxide Using Offline HPLC-MS/MS Analysis.

Brooks M Hybertson1.   

Abstract

The solubility of the vitamin E-related compound α-tocopheryl succinate in supercritical carbon dioxide was measured at pressures ranging from (15.0 to 30.0) MPa and temperatures of (40 and 50) °C using a simple microsampling type apparatus with a 100.5 μL sample loop to remove aliquots and collect them in ethanol for off line analysis. α-Tocopheryl succinate concentrations in the collected samples were measured using HPLC-MS/MS analysis. The solubility of α-tocopheryl succinate in supercritical carbon dioxide ranged from mole fractions of 0.28 × 10(-5) at 15.0 MPa and 50 °C to 2.56 × 10(-5) at 30.0 MPa and 50 °C.

Entities:  

Year:  2007        PMID: 20953319      PMCID: PMC2954408          DOI: 10.1021/je700095q

Source DB:  PubMed          Journal:  J Chem Eng Data        ISSN: 0021-9568            Impact factor:   2.694


  14 in total

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5.  Solubility of the sesquiterpene alcohol patchoulol in supercritical carbon dioxide.

Authors:  Brooks M Hybertson
Journal:  J Chem Eng Data       Date:  2007-01-01       Impact factor: 2.694

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Journal:  Nutr Cancer       Date:  1993       Impact factor: 2.900

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Authors:  Jiri Neuzil; Marco Tomasetti; Albert S Mellick; Renata Alleva; Brian A Salvatore; Marc Birringer; Marc W Fariss
Journal:  Curr Cancer Drug Targets       Date:  2004-06       Impact factor: 3.428

8.  The selective antiproliferative effects of alpha-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds.

Authors:  M W Fariss; M B Fortuna; C K Everett; J D Smith; D F Trent; Z Djuric
Journal:  Cancer Res       Date:  1994-07-01       Impact factor: 12.701

9.  Effects of tocopherol (vitamin E) acid succinate on morphological alterations and growth inhibition in melanoma cells in culture.

Authors:  K N Prasad; J Edwards-Prasad
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10.  Selective cancer cell killing by alpha-tocopheryl succinate.

Authors:  J Neuzil; T Weber; N Gellert; C Weber
Journal:  Br J Cancer       Date:  2001-01-05       Impact factor: 7.640

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