Literature DB >> 20951926

New pharmacologic therapies in gastrointestinal disease.

John L Wallace1, Jose G P Ferraz.   

Abstract

Many gastrointestinal diseases remain poorly responsive to therapies, and even in the cases of conditions for which there are many effective drugs, there is still considerable room for improvement. This article is focused on drugs for digestive disorders that have entered the marketplace recently, or are expected to reach the marketplace within the next 1 to 2 years. Although advances have been made in understanding gastrointestinal motility, visceral pain, mucosal inflammation, and tissue repair, the major gastrointestinal diseases remain as significant therapeutic challenges.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20951926     DOI： 10.1016/j.gtc.2010.08.020

Source DB:  PubMed          Journal:  Gastroenterol Clin North Am        ISSN： 0889-8553            Impact factor:   3.806


  11 in total

Review 1.  Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy.

Authors:  John L Wallace
Journal:  World J Gastroenterol       Date:  2013-03-28       Impact factor: 5.742

Review 2.  NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies.

Authors:  John L Wallace
Journal:  Br J Pharmacol       Date:  2012-01       Impact factor: 8.739

3.  Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism.

Authors:  Talita Cavalcante Morais; Synara Cavalcante Lopes; Karine Maria Martins Bezerra Carvalho; Bruno Rodrigues Arruda; Francisco Thiago Correia de Souza; Maria Teresa Salles Trevisan; Vietla Satyanarayana Rao; Flávia Almeida Santos
Journal:  World J Gastroenterol       Date:  2012-07-07       Impact factor: 5.742

4.  The Preventive Effect on Ethanol-Induced Gastric Lesions of the Medicinal Plant Plumeria rubra: Involvement of the Latex Proteins in the NO/cGMP/K ATP Signaling Pathway.

Authors:  Nylane Maria Nunes de Alencar; Rachel Sindeaux Paiva Pinheiro; Ingrid Samantha Tavares de Figueiredo; Patrícia Bastos Luz; Lyara Barbosa Nogueira Freitas; Tamiris de Fátima Goebel de Souza; Luana David do Carmo; Larisse Mota Marques; Marcio Viana Ramos
Journal:  Evid Based Complement Alternat Med       Date:  2015-12-14       Impact factor: 2.629

Review 5.  Recent Advances in NSAIDs-Induced Enteropathy Therapeutics: New Options, New Challenges.

Authors:  Yun Jeong Lim; Hoon Jai Chun
Journal:  Gastroenterol Res Pract       Date:  2013-09-12       Impact factor: 2.260

6.  Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system in vitro as well as in vivo.

Authors:  Rafik U Shaikh; Mahesh M Pund; Rajesh N Gacche
Journal:  J Tradit Complement Med       Date:  2015-08-01

7.  Chemical Constituents, Antioxidant, Cyclooxygenase Inhibitor, and Cytotoxic Activities of Teucrium pruinosum Boiss. Essential Oil.

Authors:  Nidal Jaradat; Saad Al-Lahham; Murad N Abualhasan; Abrar Bakri; Haneen Zaide; Jihan Hammad; Fatima Hussein; Linda Issa; Ahmed Mousa; Reem Speih
Journal:  Biomed Res Int       Date:  2018-07-30       Impact factor: 3.411

8.  Non-steroidal anti-inflammatory drug-induced enteropathy.

Authors:  Yun Jeong Lim; Chang-Hun Yang
Journal:  Clin Endosc       Date:  2012-06-30

9.  Advent of novel phosphatidylcholine-associated nonsteroidal anti-inflammatory drugs with improved gastrointestinal safety.

Authors:  Yun Jeong Lim; Elizabeth J Dial; Lenard M Lichtenberger
Journal:  Gut Liver       Date:  2012-11-13       Impact factor: 4.519

10.  Design, synthesis and in vivo anti-inflammatory activities of 2,4-diaryl-5-4H-imidazolone derivatives.

Authors:  Moustafa El-Araby; Abdelsattar Omar; Hassanein H Hassanein; Abdel-Ghany H El-Helby; Asharf A Abdel-Rahman
Journal:  Molecules       Date:  2012-10-18       Impact factor: 4.411
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.