| Literature DB >> 20951736 |
Behrad Noudoost1, Tirin Moore.
Abstract
We describe a modified system for the precise delivery of small volumes of drugs to brain sites of behaving monkeys during simultaneous single-neuron electrophysiology. The system combines a conventional microelectrode for recording single neurons and a small gauge microsyringe in a durable design. It incorporates newly available microfluidic components to achieve high-precision fluidic control. The system is inexpensive, reusable and easy to fabricate; it minimizes neural tissue damage and achieves reliable single-neuron recordings at the injection site. Published by Elsevier B.V.Entities:
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Year: 2010 PMID： 20951736 PMCID： PMC3161729 DOI： 10.1016/j.jneumeth.2010.10.009
Source DB: PubMed Journal: J Neurosci Methods ISSN： 0165-0270 Impact factor: 2.390