BACKGROUND: To study the epidemiology of childhood intussusception and risk factors of recurrence and operation based on a nationwide data. METHODS: Children with hospitalization due to intussusception (ICD9: 560.0) between 1998 and 2007 were identified from a national health insurance database. The incidence was calculated by age, sex, calendar year and month of admission. Recurrence and operation rates, duration and costs of hospitalization were analyzed. RESULTS: A total of 8217 intussusception-related hospitalizations were identified in 7541 children. The incidence of intussusception peaked between 3 and 36 months of age. Male -to-female incidence rate ratio increased from 1.31 in the first year to 2.52 in the ninth year of life. The overall recurrence and operation rates were 7.9% and 24.9%, respectively. In children less than 1 year old, the recurrence rate was 10.1%, which decreased to 5.3% in children over 3 years old. Multiple logistic regression analysis showed that children receiving operation had a significantly lower risk of recurrence with an odds ratio (95% confidence interval) of 0.31 (0.24-0.41) after controlling for age and sex. There are significantly more cases occurring during the warmer months between May and October compared to the cooler months between November and April. CONCLUSIONS: There was a male predominance of intussusception with a dynamic male-to-female incidence rate ratio. Children under 1 year of age have the highest recurrence and operation rates. Seasonal variation of intussusception was suspected in Taiwan.
BACKGROUND: To study the epidemiology of childhood intussusception and risk factors of recurrence and operation based on a nationwide data. METHODS:Children with hospitalization due to intussusception (ICD9: 560.0) between 1998 and 2007 were identified from a national health insurance database. The incidence was calculated by age, sex, calendar year and month of admission. Recurrence and operation rates, duration and costs of hospitalization were analyzed. RESULTS: A total of 8217 intussusception-related hospitalizations were identified in 7541 children. The incidence of intussusception peaked between 3 and 36 months of age. Male -to-female incidence rate ratio increased from 1.31 in the first year to 2.52 in the ninth year of life. The overall recurrence and operation rates were 7.9% and 24.9%, respectively. In children less than 1 year old, the recurrence rate was 10.1%, which decreased to 5.3% in children over 3 years old. Multiple logistic regression analysis showed that children receiving operation had a significantly lower risk of recurrence with an odds ratio (95% confidence interval) of 0.31 (0.24-0.41) after controlling for age and sex. There are significantly more cases occurring during the warmer months between May and October compared to the cooler months between November and April. CONCLUSIONS: There was a male predominance of intussusception with a dynamic male-to-female incidence rate ratio. Children under 1 year of age have the highest recurrence and operation rates. Seasonal variation of intussusception was suspected in Taiwan.
Authors: Lan Anh T Tran; Lay Myint Yoshida; Toyoko Nakagomi; Punita Gauchan; Koya Ariyoshi; Dang Duc Anh; Osamu Nakagomi; Vu Dinh Thiem Journal: Trop Med Health Date: 2013-08-20
Authors: Manish M Patel; Andrew D Clark; Colin F B Sanderson; Jacqueline Tate; Umesh D Parashar Journal: PLoS Med Date: 2012-10-23 Impact factor: 11.069
Authors: Lamiya Samad; Mario Cortina-Borja; Haitham El Bashir; Alastair G Sutcliffe; Sean Marven; J Claire Cameron; Richard Lynn; Brent Taylor Journal: Vaccine Date: 2013-07-17 Impact factor: 3.641