Literature DB >> 2095130

Pharmacokinetics of dimetindene after intravenous and oral administration to healthy volunteers.

V Arnera1, M Wermeille, M Wellman, J B Llull, M A Althaus, L P Balant.   

Abstract

The pharmacokinetics of dimetindene (dimethindene maleate, Fenistil, CAS 3614-69-5) were studied after its intravenous and oral administration to 8 healthy male volunteers. Serum concentrations were measured for 48 h using an enzyme-linked immunosorbent assay. Pharmacokinetic parameters (AUC, t1/2, CLs, Vd and F) were calculated using the clearance approach.

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Year:  1990        PMID: 2095130

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  Effect time-course of the inhibition of histamine induced skin reactions by orally applied dimethindene maleate.

Authors:  D Rehn; H Geissler; O Schuster; H Lukas; G Hennings
Journal:  Agents Actions       Date:  1991-05
  1 in total

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