Literature DB >> 20950904

Functional and biomechanical characteristics of foot disease in chronic gout: A case-control study.

Keith Rome1, David Survepalli, Alex Sanders, Maria Lobo, Fiona M McQueen, Peter McNair, Nicola Dalbeth.   

Abstract

OBJECTIVES: despite the predilection of gout to the feet, the impact of gout on foot function and biomechanics is currently unknown. The aim of this study was to describe the effects of chronic gout upon function and selected biomechanical parameters associated with gait.
METHODS: twenty-five patients with a history of gout were compared with 25 age and gender matched control participants with no history of gout or other forms of arthritis. General function, foot specific disease activity and lower limb activities were determined using the Health Assessment Questionnaire, Foot Function Index (pain domain), and Leeds Foot Impact Scale respectively. Each patient also underwent a gait assessment that included plantar pressure measurements and an evaluation of temporal-spatial gait parameters.
FINDINGS: patients with chronic gout had higher levels of general and foot-specific disability, pain and impairment (P ≤0.001). Significantly lower peak plantar pressures were observed in the hallux of patients with chronic gout (P ≤0.05). Significantly higher pressure-time integrals were observed in the cases at the midfoot (P ≤0.05), but lower values were observed at the hallux (P ≤0.05). Patients with chronic gout walked slower, with longer step and stride lengths compared to the controls.
INTERPRETATION: patients with chronic gout experience pain and disability associated with their feet. Different toe-off strategies may account for functional changes and pain associated with foot problems in chronic gout. 2010 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Year:  2010        PMID: 20950904     DOI: 10.1016/j.clinbiomech.2010.09.006

Source DB:  PubMed          Journal:  Clin Biomech (Bristol, Avon)        ISSN: 0268-0033            Impact factor:   2.063


  25 in total

1.  Clinical characteristics of foot ulceration in people with chronic gout.

Authors:  Keith Rome; Kathryn Erikson; Cynthia Otene; Hazra Sahid; Karyn Sangster; Peter Gow
Journal:  Int Wound J       Date:  2014-03-28       Impact factor: 3.315

2.  Physical Function, Hyperuricemia, and Gout in Older Adults.

Authors:  Bridget Teevan Burke; Anna Köttgen; Andrew Law; Beverly Gwen Windham; Dorry Segev; Alan N Baer; Josef Coresh; Mara A McAdams-DeMarco
Journal:  Arthritis Care Res (Hoboken)       Date:  2015-12       Impact factor: 4.794

Review 3.  The patient's experience of gout: new insights to optimize management.

Authors:  Nicola Dalbeth; Karen Lindsay
Journal:  Curr Rheumatol Rep       Date:  2012-04       Impact factor: 4.592

Review 4.  Mechanisms of joint damage in gout: evidence from cellular and imaging studies.

Authors:  Fiona M McQueen; Ashika Chhana; Nicola Dalbeth
Journal:  Nat Rev Rheumatol       Date:  2012-01-10       Impact factor: 20.543

5.  Risk factors for ulceration over tophi in patients with gout.

Authors:  Jianjun Xu; Cai Lin; Peng Zhang; Jianghui Ying
Journal:  Int Wound J       Date:  2016-10-10       Impact factor: 3.315

6.  Effects of worn and new footwear on plantar pressure in people with gout.

Authors:  Mike Frecklington; Nicola Dalbeth; Peter McNair; Alain Vandal; Peter Gow; Keith Rome
Journal:  BMC Musculoskelet Disord       Date:  2021-05-24       Impact factor: 2.362

7.  Gout and 'Podagra' in medieval Cambridge, England.

Authors:  Jenna M Dittmar; Piers D Mitchell; Peter M Jones; Bram Mulder; Sarah A Inskip; Craig Cessford; John E Robb
Journal:  Int J Paleopathol       Date:  2021-05-04       Impact factor: 1.448

8.  Prospective observational cohort study of Health Related Quality of Life (HRQOL), chronic foot problems and their determinants in gout: a research protocol.

Authors:  Priyanka Chandratre; Christian Mallen; Jane Richardson; Keith Rome; Joanne Bailey; Rajvinder Gill; Samantha Hider; Jane Mason; Zoe Mayson; Sara Muller; Charlotte Purcell; Jennifer Titley; Simon Wathall; Irena Zwierska; Edward Roddy
Journal:  BMC Musculoskelet Disord       Date:  2012-11-13       Impact factor: 2.362

9.  Revisiting the pathogenesis of podagra: why does gout target the foot?

Authors:  Edward Roddy
Journal:  J Foot Ankle Res       Date:  2011-05-13       Impact factor: 2.303

10.  An evaluation of seasonal variations in footwear worn by adults with inflammatory arthritis: a cross-sectional observational study using a web-based survey.

Authors:  Angela Brenton-Rule; Gordon J Hendry; Georgina Barr; Keith Rome
Journal:  J Foot Ankle Res       Date:  2014-08-13       Impact factor: 2.303

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