Literature DB >> 20950309

Laparoscopic extended pelvic lymph node dissection during radical cystectomy: technique and clinical outcomes.

Pengfei Shao1, Xiaoxin Meng, Jie Li, Qiang Lv, Wei Zhang, Zhengquan Xu, Changjun Yin.   

Abstract

OBJECTIVE: • To study the surgical techniques and clinical results of laparoscopic extended pelvic lymph node dissection during radical cystectomy. PATIENTS AND METHODS: • From July 2007 to October 2009, 43 patients with bladder carcinoma received laparoscopic radical cystectomy with extended pelvic lymphadenectomy and urinary diversion. • Pelvic lymph node dissection (PLND) was first performed within extended template. • The lower part of aorta and vena cava were isolated from the bifurcation of common iliac artery to the level of the inferior mesenteric artery. • The standard template PLND was continued along the external iliac vessels, internal iliac vessels and obturator nerve. The bladder was then removed laparoscopically and urinary diversion was performed.
RESULTS: • All procedures were performed successfully and no open conversion occurred. The duration of the procedure for extended PLND was 90-185 min (mean 125 min) and total duration was 280-470 min (mean 329 min). • Intra-operative blood loss was 200-1500 mL (mean 325 mL) and eight cases received transfusion. Pathological study identified transitional cell carcinoma and a negative margin in all cases. A range of 19-53 lymph nodes were dissected in the patients with a mean of 31.3. • In total, 17 positive nodes were confirmed in 11 cases. Postoperative complications included two cases of bowel obstruction, two cases of mild urine leakage and 17 cases of lymphatic leakage.
CONCLUSIONS: • Laparoscopic radical cystectomy with extended pelvic lymphadenectomy is indicated in selected patients with bladder cancer. • It is safe, minimally invasive and more lymph nodes can be retrieved with a higher success rate by extended pelvic lymphadenectomy.
© 2010 THE AUTHORS. BJU INTERNATIONAL © 2010 BJU INTERNATIONAL.

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Year:  2010        PMID: 20950309     DOI: 10.1111/j.1464-410X.2010.09774.x

Source DB:  PubMed          Journal:  BJU Int        ISSN: 1464-4096            Impact factor:   5.588


  7 in total

1.  Simultaneous robot-assisted radical cystoprostatectomy and nephroureterectomy in a patient with multifocal invasive urothelial carcinoma and previous contralateral nephroureterectomy.

Authors:  Bora Özveren; Levent Türkeri
Journal:  J Robot Surg       Date:  2012-09-19

2.  MiRNA-141 and miRNA-200b are closely related to invasive ability and considered as decision-making biomarkers for the extent of PLND during cystectomy.

Authors:  Wentao Liu; Lin Qi; Hui Lv; Xiongbing Zu; Minfeng Chen; Jun Wang; Longfei Liu; Feng Zeng; Yuan Li
Journal:  BMC Cancer       Date:  2015-03-04       Impact factor: 4.430

3.  Upregulation of Arp2 expression is associated with the prognosis and prediction of lymph node metastasis in bladder urothelial carcinoma.

Authors:  Ning Xu; Gen-Yi Qu; Yu-Peng Wu; Xiao-Dong Li; Min-Yi Lin; Shao-Hao Chen; Xue-Yi Xue; Yong Wei
Journal:  Cancer Manag Res       Date:  2018-03-19       Impact factor: 3.989

Review 4.  The evolving role of lymphadenectomy for bladder cancer: why, when, and how.

Authors:  Vignesh T Packiam; Matvey Tsivian; Stephen A Boorjian
Journal:  Transl Androl Urol       Date:  2020-12

Review 5.  The Usefulness of Lymphadenectomy in Bladder Cancer-Current Status.

Authors:  Bartosz Małkiewicz; Paweł Kiełb; Adam Gurwin; Klaudia Knecht; Karol Wilk; Jakub Dobruch; Romuald Zdrojowy
Journal:  Medicina (Kaunas)       Date:  2021-04-25       Impact factor: 2.430

Review 6.  Laparoscopic radical cystectomy.

Authors:  Amr Fergany
Journal:  Arab J Urol       Date:  2012-02-20

Review 7.  A review of the postoperative lymphatic leakage.

Authors:  Shulan Lv; Qing Wang; Wanqiu Zhao; Lu Han; Qi Wang; Nasra Batchu; Qurat Ulain; Junkai Zou; Chao Sun; Jiang Du; Qing Song; Qiling Li
Journal:  Oncotarget       Date:  2017-04-20
  7 in total

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