Peter A Newcombe1, Jeanie K Sheffield2, Anne B Chang3. 1. School of Social Work and Applied Human Sciences, University of Queensland, Brisbane, QLD; School of Psychology, University of Queensland, Brisbane, QLD. Electronic address: newc@psy.uq.edu.au. 2. School of Psychology, University of Queensland, Brisbane, QLD. 3. Queensland Children's Respiratory Centre and Queensland Children's Medical Research Institute, Royal Children's Hospital, Brisbane, QLD; Child Health Division, Menzies School of Health Research, Darwin, NT, Australia.
Abstract
BACKGROUND: The Parent Cough-Specific Quality-of-Life questionnaire (PC-QOL) has relevance and clinical utility as a cough-specific QOL measure for pediatric use. Its validity has been demonstrated. This study sought to determine the minimally important difference (MID) for the PC-QOL completed by parents of young children with chronic cough. METHOD: Thirty-four children (22 boys, 12 girls; median age, 26.5 months; interquartile range, 17.3-38.8 months) and their mothers participated. Mothers completed a cough-related measure (verbal category descriptive score) and the PC-QOL on two occasions separated by 2 to 3 weeks. Two approaches were used to calculate MID. RESULTS: Distribution-based approaches to estimating MID resulted in ranges of 0.50 to 0.78 (effect size method), 0.30 to 0.48 (SE of measurement method), and 0.60 to 0.69 (one-half SD method) for PC-QOL overall and domain scales. Based on verbal category descriptive score change, an anchor-based approach resulted in an MID estimate of 0.9 for overall PC-QOL change and ranged from 0.71 to 0.95 for individual domain PC-QOL change. CONCLUSION: An MID for the PC-QOL of 0.9 is recommended in interpreting health status change in children with chronic cough and will aid clinicians and researchers in interpreting health-related QOL changes following treatments and clinical trials.
BACKGROUND: The Parent Cough-Specific Quality-of-Life questionnaire (PC-QOL) has relevance and clinical utility as a cough-specific QOL measure for pediatric use. Its validity has been demonstrated. This study sought to determine the minimally important difference (MID) for the PC-QOL completed by parents of young children with chronic cough. METHOD: Thirty-four children (22 boys, 12 girls; median age, 26.5 months; interquartile range, 17.3-38.8 months) and their mothers participated. Mothers completed a cough-related measure (verbal category descriptive score) and the PC-QOL on two occasions separated by 2 to 3 weeks. Two approaches were used to calculate MID. RESULTS: Distribution-based approaches to estimating MID resulted in ranges of 0.50 to 0.78 (effect size method), 0.30 to 0.48 (SE of measurement method), and 0.60 to 0.69 (one-half SD method) for PC-QOL overall and domain scales. Based on verbal category descriptive score change, an anchor-based approach resulted in an MID estimate of 0.9 for overall PC-QOL change and ranged from 0.71 to 0.95 for individual domain PC-QOL change. CONCLUSION: An MID for the PC-QOL of 0.9 is recommended in interpreting health status change in children with chronic cough and will aid clinicians and researchers in interpreting health-related QOL changes following treatments and clinical trials.
Authors: Louis-Philippe Boulet; Remy R Coeytaux; Douglas C McCrory; Cynthia T French; Anne B Chang; Surinder S Birring; Jaclyn Smith; Rebecca L Diekemper; Bruce Rubin; Richard S Irwin Journal: Chest Date: 2015-03 Impact factor: 9.410
Authors: Anne B Chang; Keith Grimwood; Colin F Robertson; Andrew C Wilson; Peter P van Asperen; Kerry-Ann F O'Grady; Theo P Sloots; Paul J Torzillo; Emily J Bailey; Gabrielle B McCallum; Ian B Masters; Catherine A Byrnes; Mark D Chatfield; Helen M Buntain; Ian M Mackay; Peter S Morris Journal: Trials Date: 2012-08-31 Impact factor: 2.279
Authors: Vikas Goyal; Keith Grimwood; Robert S Ware; Catherine A Byrnes; Peter S Morris; I Brent Masters; Gabrielle B McCallum; Michael J Binks; Heidi Smith-Vaughan; Kerry-Ann F O'Grady; Anita Champion; Helen M Buntain; André Schultz; Mark Chatfield; Paul J Torzillo; Anne B Chang Journal: Lancet Respir Med Date: 2019-08-16 Impact factor: 30.700
Authors: Anne B Chang; Keith Grimwood; Andrew C Wilson; Peter P van Asperen; Catherine A Byrnes; Kerry-Ann F O'Grady; Theo P Sloots; Colin F Robertson; Paul J Torzillo; Gabrielle B McCallum; Ian B Masters; Helen M Buntain; Ian M Mackay; Jacobus Ungerer; Joanne Tuppin; Peter S Morris Journal: Trials Date: 2013-02-20 Impact factor: 2.279
Authors: Alessandro Zanasi; Salvatore Cazzato; Massimiliano Mazzolini; Carla Maria Sofia Ierna; Marianna Mastroroberto; Elena Nardi; Antonio Maria Morselli-Labate Journal: Multidiscip Respir Med Date: 2015-08-07
Authors: Anne B Chang; John W Upham; I Brent Masters; Gregory R Redding; Peter G Gibson; Julie M Marchant; Keith Grimwood Journal: Pediatr Pulmonol Date: 2015-12-04
Authors: Vikas Goyal; Keith Grimwood; Catherine A Byrnes; Peter S Morris; I Brent Masters; Robert S Ware; Gabrielle B McCallum; Michael J Binks; Julie M Marchant; Peter van Asperen; Kerry-Ann F O'Grady; Anita Champion; Helen M Buntain; Helen Petsky; Paul J Torzillo; Anne B Chang Journal: Lancet Date: 2018-09-18 Impact factor: 79.321