Literature DB >> 20947007

The talin FERM domain is not so FERM.

Iain D Campbell1.   

Abstract

The structure of the head domain of talin, an intracellular activator of integrin membrane adhesion receptors, has been solved by Elliott et al. (2010). A FERM domain can be identified in the head from sequence comparisons but, rather than having a compact structure of three subdomains, it has linear arrangement of four subdomains.
Copyright © 2010 Elsevier Ltd. All rights reserved.

Year:  2010        PMID: 20947007     DOI: 10.1016/j.str.2010.09.002

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  4 in total

1.  A distinct talin2 structure directs isoform specificity in cell adhesion.

Authors:  Erumbi S Rangarajan; Marina C Primi; Lesley A Colgan; Krishna Chinthalapudi; Ryohei Yasuda; Tina Izard
Journal:  J Biol Chem       Date:  2020-06-30       Impact factor: 5.157

2.  Talin1 and Rap1 are critical for osteoclast function.

Authors:  Wei Zou; Takashi Izawa; Tingting Zhu; Jean Chappel; Karel Otero; Susan J Monkley; David R Critchley; Brian G Petrich; Alexei Morozov; Mark H Ginsberg; Steven L Teitelbaum
Journal:  Mol Cell Biol       Date:  2012-12-10       Impact factor: 4.272

3.  Phosphatidylinositol 4,5-Bisphosphate Modulates the Affinity of Talin-1 for Phospholipid Bilayers and Activates Its Autoinhibited Form.

Authors:  Xin Ye; Mark A McLean; Stephen G Sligar
Journal:  Biochemistry       Date:  2016-08-31       Impact factor: 3.162

4.  Conformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helices.

Authors:  Antreas C Kalli; Iain D Campbell; Mark S P Sansom
Journal:  PLoS Comput Biol       Date:  2013-10-31       Impact factor: 4.779

  4 in total

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