Literature DB >> 20944943

[Peter's anomaly, clinical and therapeutic aspects: case report].

Isadora Meyer1, Hévila Rolim, Afonso Medeiros, Luciano Paiva, Roberto Galvão Filho.   

Abstract

Peter's anomaly consists in the most common congenital corneal opacity related to a malformation of the anterior segment of the eye. Its main characteristics are central leukoma and iridocorneal adherences at the area affected by the leukoma. It can be identified isolated or in association with other ocular or systemic abnormalities, and the prognostic tend to be worse in the latter cases. The etiology of Peter's anomaly remains uncertain, but the most likely causes are related to genetic, infectious, traumatic and toxic factors. A range of possible treatment strategies exists, though the effectiveness of each of them depends on how the disease occurs and whether it is identified in early or advanced stages - the earlier the diagnosis, the higher the possibility of a successful intervention, given that precocious treatments are more likely to result in a good development of the vision. This work reports a case of Peter's anomaly that was diagnosed in an advanced stage, discussing the characteristics of the case and treatment possibilities.

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Year:  2010        PMID: 20944943     DOI: 10.1590/s0004-27492010000400014

Source DB:  PubMed          Journal:  Arq Bras Oftalmol        ISSN: 0004-2749            Impact factor:   0.872


  2 in total

1.  Loss of Msx2 function down-regulates the FoxE3 expression and results in anterior segment dysgenesis resembling Peters anomaly.

Authors:  Jiangyue Zhao; Kirio Kawai; Hongyan Wang; Di Wu; Mingwu Wang; Zhicao Yue; Jinsong Zhang; Yi-Hsin Liu
Journal:  Am J Pathol       Date:  2012-04-13       Impact factor: 4.307

2.  Interaction between Pax6 and its novel mutant in Bufo raddei Strauch.

Authors:  Furong Ju; Yongqing Zhao; Yuanlin Zhao; Ying Wang; Fan Wen; Lin Ye; Lan Gao
Journal:  Mol Vis       Date:  2011-10-18       Impact factor: 2.367

  2 in total

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