| Literature DB >> 20943040 |
M L Castellani, P Felaco, R J Galzio, D Tripodi, E Toniato, M A De Lutiis, M Fulcheri, A Caraffa, P Antinolfi, S Tetè, M Felaco, F Conti, F Pandolfi, T C Theoharides, Y B Shaik-Dasthagirisaheb.
Abstract
Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its surface receptor. This cytokine is also produced by mast cells and mast cell line, suggesting a role in allergic diseases. In this editorial we revisit the biological role of IL-31 in immunity and inflammation.Entities:
Mesh：
Substances：
Year: 2010 PMID： 20943040 DOI： 10.1177/039463201002300304
Source DB: PubMed Journal: Int J Immunopathol Pharmacol ISSN： 0394-6320 Impact factor: 3.219