Chemistry of methylcorrinoids related to their roles in bacterial C1 metabolism.

Corrinoids are central cofactors in bacterial metabolism, where they participate in a series of organometallic and redoxprocesses. These depend on the unique coordination chemistry and reactivity of the corrin-bound cobalt centers to which, in the complete corrins, also a nucleotide function can coordinate intramolecularly. The roles of methylcorrinoids in bacterial C1 metabolism focus around the unusual Co-C-bond.