Mi Kyung Kim1, Min Jung Ko, Jun Tae Han. 1. Department of Preventive Medicine, Hanyang University, College of Medicine, Medical School Building A, Room 512, 17 Haengdang Dong, Sungdong Gu, Seoul 133-791, Republic of Korea. kmkkim@hanyang.ac.kr
Abstract
BACKGROUND: The relationship between alcohol and cancer death has not been well established in Asian population, particularly among women. METHOD: We evaluated the association between alcohol consumption and all-cause and cancer mortality in a large-scale prospective study of 1,341,393 Korean men and women aged 40-69 years who participated in health examination in 2000. After 5 years follow-up for mortality (2001-2005), 19,375 deaths were identified, and Cox regression was used for longitudinal analyses. RESULTS: The J-shaped relationship between alcohol consumption and all-cause and all-cancer mortality was found in men. However, heavy drinking was positively associated with the risk of all-cause and all-cancer mortality in men and women. Alcohol consumption was positively associated with the risk of cancer mortality such as cancers of liver, stomach, colorectal, prostate, esophageal, brain, and larynx and cancer of lips, oral cavity, pharynx in men and increased the risk of all-cancer and colorectal cancer mortality in women. Kidney cancer mortality was inversely associated with alcohol consumption in men. CONCLUSION: Heavy drinking showed an increased mortality risk of all-cause, all-cancer, and several cancers in men and women. There was no favorable effect of light drinking on all-cause and all-cancer mortality for women.
BACKGROUND: The relationship between alcohol and cancer death has not been well established in Asian population, particularly among women. METHOD: We evaluated the association between alcohol consumption and all-cause and cancer mortality in a large-scale prospective study of 1,341,393 Korean men and women aged 40-69 years who participated in health examination in 2000. After 5 years follow-up for mortality (2001-2005), 19,375 deaths were identified, and Cox regression was used for longitudinal analyses. RESULTS: The J-shaped relationship between alcohol consumption and all-cause and all-cancer mortality was found in men. However, heavy drinking was positively associated with the risk of all-cause and all-cancer mortality in men and women. Alcohol consumption was positively associated with the risk of cancer mortality such as cancers of liver, stomach, colorectal, prostate, esophageal, brain, and larynx and cancer of lips, oral cavity, pharynx in men and increased the risk of all-cancer and colorectal cancer mortality in women. Kidney cancer mortality was inversely associated with alcohol consumption in men. CONCLUSION: Heavy drinking showed an increased mortality risk of all-cause, all-cancer, and several cancers in men and women. There was no favorable effect of light drinking on all-cause and all-cancer mortality for women.
Authors: David J Cote; Claudine M Samanic; Timothy R Smith; Molin Wang; Stephanie A Smith-Warner; Meir J Stampfer; Kathleen M Egan Journal: Eur J Epidemiol Date: 2021-09-04 Impact factor: 12.434
Authors: David J Cote; Timothy R Smith; Ursula B Kaiser; Edward R Laws; Meir J Stampfer Journal: Cancer Causes Control Date: 2022-01-04 Impact factor: 2.532
Authors: Shao-Ming Wang; Hormuzd A Katki; Barry I Graubard; Lisa L Kahle; Anil Chaturvedi; Charles E Matthews; Neal D Freedman; Christian C Abnet Journal: Am J Gastroenterol Date: 2021-09-01 Impact factor: 12.045