Christfried Jakob's 1921 Theory of the Gnoses and Praxes as fundamental factors in cerebral cortical dynamics.

This study aims at reviving an important contribution by the pioneer neurobiologist and neurophilosopher Christfried Jakob (1866-1956) to the understanding of higher cortical functions. Jakob studied cortical dynamics at multiple levels by comparing gnoses and praxes and their corresponding pathological states, i.e. the agnosias and the apraxias. We herein provide a complete English translation of Jakob's original Spanish article dating to 1921, and further consider some key points under the scope of the neuropsychological knowledge available then, and the research evidence available 90 years later.