CONTEXT: Perioperative blood transfusions are costly and have safety concerns. As a result, there have been multiple initiatives to reduce transfusion use. However, the degree to which perioperative transfusion rates vary among hospitals is unknown. OBJECTIVE: To assess hospital-level variation in use of allogeneic red blood cell (RBC), fresh-frozen plasma, and platelet transfusions in patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN, SETTING, AND PATIENTS: An observational cohort of 102,470 patients undergoing primary isolated CABG surgery with cardiopulmonary bypass during calendar year 2008 at 798 sites in the United States, contributing data to the Society of Thoracic Surgeons Adult Cardiac Surgery Database. MAIN OUTCOME MEASURES: Perioperative (intraoperative and postoperative) transfusion of RBCs, fresh-frozen plasma, and platelets. RESULTS: At hospitals performing at least 100 on-pump CABG operations (82,446 cases at 408 sites), the rates of blood transfusion ranged from 7.8% to 92.8% for RBCs, 0% to 97.5% for fresh-frozen plasma, and 0.4% to 90.4% for platelets. Multivariable analysis including data from all 798 sites (102,470 cases) revealed that after adjustment for patient-level risk factors, hospital transfusion rates varied by geographic location (P = .007), academic status (P = .03), and hospital volume (P < .001). However, these 3 hospital characteristics combined only explained 11.1% of the variation in hospital risk-adjusted RBC usage. Case mix explained 20.1% of the variation between hospitals in RBC usage. CONCLUSION: Wide variability occurred in the rates of transfusion of RBCs and other blood products, independent of case mix, among patients undergoing CABG surgery with cardiopulmonary bypass in US hospitals in an adult cardiac surgical database.
CONTEXT: Perioperative blood transfusions are costly and have safety concerns. As a result, there have been multiple initiatives to reduce transfusion use. However, the degree to which perioperative transfusion rates vary among hospitals is unknown. OBJECTIVE: To assess hospital-level variation in use of allogeneic red blood cell (RBC), fresh-frozen plasma, and platelet transfusions in patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN, SETTING, AND PATIENTS: An observational cohort of 102,470 patients undergoing primary isolated CABG surgery with cardiopulmonary bypass during calendar year 2008 at 798 sites in the United States, contributing data to the Society of Thoracic Surgeons Adult Cardiac Surgery Database. MAIN OUTCOME MEASURES: Perioperative (intraoperative and postoperative) transfusion of RBCs, fresh-frozen plasma, and platelets. RESULTS: At hospitals performing at least 100 on-pump CABG operations (82,446 cases at 408 sites), the rates of blood transfusion ranged from 7.8% to 92.8% for RBCs, 0% to 97.5% for fresh-frozen plasma, and 0.4% to 90.4% for platelets. Multivariable analysis including data from all 798 sites (102,470 cases) revealed that after adjustment for patient-level risk factors, hospital transfusion rates varied by geographic location (P = .007), academic status (P = .03), and hospital volume (P < .001). However, these 3 hospital characteristics combined only explained 11.1% of the variation in hospital risk-adjusted RBC usage. Case mix explained 20.1% of the variation between hospitals in RBC usage. CONCLUSION: Wide variability occurred in the rates of transfusion of RBCs and other blood products, independent of case mix, among patients undergoing CABG surgery with cardiopulmonary bypass in US hospitals in an adult cardiac surgical database.
Authors: Babikir Kheiri; Ahmed Abdalla; Mohammed Osman; Tarek Haykal; Sai Chintalapati; James Cranford; Jason Sotzen; Meghan Gwinn; Sahar Ahmed; Mustafa Hassan; Ghassan Bachuwa; Deepak L Bhatt Journal: J Thromb Thrombolysis Date: 2019-02 Impact factor: 2.300
Authors: Donald S Likosky; Robert A Baker; Timothy A Dickinson; Daniel J FitzGerald; M Filip De Somer; Robert C Groom; David FitzGerald; Kenneth G Shann; Michael Poullis; Bruce D Spiess; Karim Jabr; Mark T Lucas; James D Ferguson; Shahna L Bronson Journal: J Extra Corpor Technol Date: 2015-06
Authors: Juan B Grau; Jacqueline H Fortier; Cyrus Kuschner; Giovanni Ferrari; Mariano E Brizzio; Alex Zapolanski; Richard E Shaw Journal: Transfusion Date: 2017-07-16 Impact factor: 3.157
Authors: Anton Camaj; Darin B Zahuranec; Gaetano Paone; Barbara R Benedetti; Warren D Behr; Marc A Zimmerman; Min Zhang; Robert S Kramer; Jason Penn; Patricia F Theurer; Theron A Paugh; Milo Engoren; Alphonse DeLucia; Richard L Prager; Donald S Likosky Journal: Anesth Analg Date: 2017-09 Impact factor: 5.108
Authors: Jarrod E Dalton; David A Zidar; Belinda L Udeh; Manesh R Patel; Jesse D Schold; Neal V Dawson Journal: Med Care Date: 2016-06 Impact factor: 2.983
Authors: Richard E Shaw; Christopher K Johnson; Giovanni Ferrari; Alex Zapolanski; Mariano Brizzio; Nancy Rioux; Srinivasa Edara; Jason Sperling; Juan B Grau Journal: Interact Cardiovasc Thorac Surg Date: 2013-03-28
Authors: Osman N Salaria; Viachaslau M Barodka; Charles W Hogue; Dan E Berkowitz; Paul M Ness; Jack O Wasey; Steven M Frank Journal: Anesth Analg Date: 2014-06 Impact factor: 5.108