Acceptance of the neuron theory by clinical neurologists of the late-nineteenth century.

This article explores reactions of clinical neurologists of the late-nineteenth century to the concept of a unified nerve cell, the "neuron," which developed from the research on fine anatomy of the nervous system and from conclusions of Waldeyer based on that research. Assessment shows that Waldeyer's role in the acceptance of the neuron theory was not straightforward. A study of primarily American medical literature shows rapid acceptance, eager applications, and high expectations. Nonetheless, some clinicians were disappointed in its immediate relevance. An explanation for this disappointment is offered.