Literature DB >> 20938628

[54-year-old male with hepatic cirrhosis and therapy-associated torsade de pointes tachycardia].

M Lehmann1, T Bruns, A Herrmann, M Fritzenwanger, A Stallmach.   

Abstract

We present a case of a patient with newly diagnosed cirrhosis and kidney failure who underwent cardiopulmonary resuscitation twice after treatment with terlipressin. After the second application a QT interval prolongation and torsade de pointes were documented. Since other causes were excluded, we interpret both events as terlipressin-induced ventricular arrhythmia. Therefore, it seems important to consider this rare but potentially lethal side effect when administering this drug to patients.

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Year:  2011        PMID: 20938628     DOI: 10.1007/s00108-010-2667-5

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  9 in total

Review 1.  Drug-induced prolongation of the QT interval.

Authors:  Dan M Roden
Journal:  N Engl J Med       Date:  2004-03-04       Impact factor: 91.245

Review 2.  Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis.

Authors:  Francesco Salerno; Alexander Gerbes; Pere Ginès; Florence Wong; Vicente Arroyo
Journal:  Gut       Date:  2007-03-27       Impact factor: 23.059

3.  Comparative cardiac effects of terlipressin, vasopressin, and norepinephrine on an isolated perfused rabbit heart.

Authors:  Alexandre Ouattara; Marc Landi; Yannick Le Manach; Patrick Lecomte; Morgan Leguen; Gilles Boccara; Pierre Coriat; Bruno Riou
Journal:  Anesthesiology       Date:  2005-01       Impact factor: 7.892

4.  Effects of terlipressin on systemic, hepatic and renal hemodynamics in patients with cirrhosis.

Authors:  Yoshiyuki Narahara; Hidenori Kanazawa; Yasuhiko Taki; Yuu Kimura; Masanori Atsukawa; Tamaki Katakura; Hideko Kidokoro; Hirotomo Harimoto; Takeshi Fukuda; Yoko Matsushita; Katsuhisa Nakatsuka; Choitsu Sakamoto
Journal:  J Gastroenterol Hepatol       Date:  2009-08-03       Impact factor: 4.029

5.  Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage. Variceal Bleeding Study Group.

Authors:  F Feu; L Ruiz del Arbol; R Bañares; R Planas; J Bosch
Journal:  Gastroenterology       Date:  1996-11       Impact factor: 22.682

Review 6.  Vasopressin and terlipressin: pharmacology and its clinical relevance.

Authors:  P C A Kam; S Williams; F F Y Yoong
Journal:  Anaesthesia       Date:  2004-10       Impact factor: 6.955

7.  Terlipressin therapy for renal failure in cirrhosis.

Authors:  Christos K Triantos; Dimitrios Samonakis; Ulrich Thalheimer; Evangelos Cholongitas; Marco Senzolo; Laura Marelli; Gioacchino Leandro; David Patch; Andrew K Burroughs
Journal:  Eur J Gastroenterol Hepatol       Date:  2010-04       Impact factor: 2.566

8.  A randomized, prospective, double-blind, placebo-controlled trial of terlipressin for type 1 hepatorenal syndrome.

Authors:  Arun J Sanyal; Thomas Boyer; Guadalupe Garcia-Tsao; Frederick Regenstein; Lorenzo Rossaro; Beate Appenrodt; Andres Blei; Veit Gülberg; Samuel Sigal; Peter Teuber
Journal:  Gastroenterology       Date:  2008-02-13       Impact factor: 22.682

9.  Terlipressin-induced ventricular arrhythmia.

Authors:  Ján Urge; Frantisek Sincl; Vlastimil Procházka; Karel Urbánek
Journal:  Scand J Gastroenterol       Date:  2008       Impact factor: 2.423

  9 in total
  1 in total

Review 1.  Arrhythmia risk in liver cirrhosis.

Authors:  Ioana Mozos
Journal:  World J Hepatol       Date:  2015-04-08
  1 in total

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