Literature DB >> 20938119

[A case of hemolytic uremic syndrome after adjuvant chemotherapy with gemcitabine in a patient with pancreatic cancer].

Masaki Wato1, Tomoki Inaba, Hisashi Ishikawa, Shigenao Ishikawa, Nobuyuki Baba, Masatsugu Miyoshi, Tomonori Senoh, Takuya Nagano, Koichi Takaguchi, Seishiro Watanabe, Kozo Kawai.   

Abstract

A 63-year-old man with Stage IVa pancreas tail cancer was admitted for a distal pancreatectomy and splenectomy; adjuvant chemotherapy with gemcitabine was also administered. The chemotherapy was terminated after 16 courses due to hemolytic anemia, thrombocytopenia and renal dysfunction. Plasma exchange was performed; however the patient's renal function was diminished, requiring chronic hemodialysis. Physicians should be cautious of hemolytic uremic syndrome as a possible adverse reaction to gemcitabine and be aware that tests are needed for its early detection.

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Year:  2010        PMID: 20938119

Source DB:  PubMed          Journal:  Nihon Shokakibyo Gakkai Zasshi        ISSN: 0446-6586


  2 in total

1.  Gemcitabine-induced haemolytic uraemic syndrome in pancreatic adenocarcinoma.

Authors:  Adarsh Das; Andrew Dean; Tim Clay
Journal:  BMJ Case Rep       Date:  2019-04-08

Review 2.  Gemcitabine-induced hemolytic uremic syndrome in pancreatic cancer: a case report and review of the literature.

Authors:  Hye Won Lee; Moon Jae Chung; Huapyong Kang; Heun Choi; Youn Jeong Choi; Kyung Joo Lee; Seung Woo Lee; Seung Hyuk Han; Jin Seok Kim; Si Young Song
Journal:  Gut Liver       Date:  2014-01-13       Impact factor: 4.519

  2 in total

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