Developmental trajectories of child to adolescent externalizing behavior and adult DSM-IV disorder: results of a 24-year longitudinal study.

OBJECTIVE: Childhood externalizing behavior is found to be relatively persistent. Developmental pathways within types of externalizing behavior have been recognized from childhood to adolescence. We aimed to describe the prediction of adult DSM-IV disorders from developmental trajectories of externalizing behavior over a period of 24 years on a longitudinal multiple birth cohort study of 2,076 children. This has not been examined yet.
METHODS: Trajectories of the four externalizing behavior types aggression, opposition, property violations, and status violations were determined separately through latent class growth analysis (LCGA) using data of five waves, covering ages 4-18 years. Psychiatric disorders of 1,399 adults were assessed with the CIDI. We used regression analyses to determine the associations between children's trajectories and adults' psychiatric disorders.
RESULTS: All externalizing behavior types showed significant associations with disruptive disorder in adulthood. In all antisocial behavior types high-level trajectories showed the highest probability for predicting adult disorders. Particularly the status violations cluster predicted many disorders in adulthood. The trajectories most often predicted disruptive disorders in adulthood, but predicted also anxiety, mood, and substance use disorders.
CONCLUSIONS: We can conclude that an elevated level of externalizing behavior in childhood has impact on the long-term outcome, regardless of the developmental course of externalizing behavior. Furthermore, different types of externalizing behavior (i.e., aggression, opposition, property violations, and status violations) were related to different adult outcomes, and children and adolescents with externalizing behavior of the status violations subtype were most likely to be affected in adulthood.

Introduction

It is well established in the literature that externalizing behavior in childhood and adolescence is associated with a wide range of poor concurrent and longitudinal outcomes [1]. Regarding longitudinal outcomes, studies report that children and adolescents with externalizing behavior problems are at risk for a wide range of disorders in adulthood that include: disruptive behavior [2-7], mood and anxiety problems [8-11], and substance use and abuse [5, 9, 12].

However, because externalizing behavior is an umbrella concept encompassing several different kinds of behavior, Frick et al. [13] performed a meta-analysis of 44 published studies and empirically divided externalizing behavior into four types: aggression (e.g., fights, bullies), oppositionality (e.g., temper, stubborn), property violations (e.g., lies, cruel to animals), and status violations (e.g., substance use, runaway). To our knowledge, only two studies have examined the adult outcome of types of externalizing behavior problems as suggested by Frick and colleagues [13]. These studies underline the need to distinguish between types of externalizing behavior, that is, they report that status violations predict substance use and social impairment, that oppositionality only predicts social impairment, whereas property violations and aggression predict both substance use and risky sexual behavior [15, 16].

Regarding development of externalizing behavior, previous studies have provided evidence for variation in developmental trajectories of externalizing behavior in childhood and adolescence with most studies identifying four to six distinctive trajectories [17-19]. Developmental trajectories describe changes in both the level and the growth or decline of behaviors over time [20]. It is important to know which change in level and growth across age may be considered normative for children and adolescents. Because from both theoretical and clinical perspective, it is indispensable to understand normal development for defining abnormal behavior at any age point. In the previous study that examined the development of the four externalizing behavior types suggested by Frick et al. [13] from early childhood up to young adulthood (i.e., from age 4 to age 18) the following developmental trajectories were identified: three trajectories for aggression ranging from very low to high, six trajectories for oppositionality ranging from very low to high and including a trajectory where oppositionality increased in adolescence, and four trajectories for property and status violation ranging from low to high [21]. Considering these different developmental trajectories of externalizing behavior that groups of children follow, it is important to examine groups of children that follow developmental trajectories that vary in level and shape, because an average developmental trajectory that describes expected development for most children may be considered insufficient. In the current study, we determined distinctive groups of individuals who are more likely to follow one developmental trajectory than another, within each type of externalizing behavior.

In the study by Bongers et al. [21], status violations was the only externalizing behavior type that increased with age, whereas the remaining types primarily showed a persisting or decreasing course. In a more recent study by Bongers et al. [15], in which the relation of both level and growth of externalizing problems, as suggested by Frick et al. [13], to adult outcomes was examined, primarily the level of the trajectories was found to be predictive. Children with high-level trajectories of opposition and status violations reported more impaired social functioning, regardless of the direction, or growth, or decline of these high-level trajectories. However, in the study by Timmermans et al. [16] both the level and growth of opposition, aggression, and property violations were related to poor adolescent outcomes such as risky sexual behavior and substance use. In this latter study only the level of status violations predicted later negative outcomes. Hence, findings are inconclusive as to how developmental trajectories of these externalizing behavior types are related to other long-term outcomes, and further research on this issue is needed.

In this study, we aimed to investigate associations between childhood externalizing behavior and adult psychopathology. We examined the prediction of adult DSM-IV disorders from developmental trajectories of the four types of externalizing behavior suggested by Frick et al. [13] (i.e., opposition, aggression, property violations, and status violations) over a period of 24 years in a longitudinal, multiple birth cohort study of 2,076 children from the general population. Because studies have reported prognostic differences between the four types of childhood externalizing behavior as suggested by Frick et al. [13], we investigated the linkage between childhood externalizing behavior and adult psychopathology, distinguishing these types of externalizing behavior. In addition, although previous studies reported outcomes for the four externalizing behavior types up to young adulthood (i.e., age 18 in the study by Timmermans et al. [16]; up to age 30 in the study by Bongers et al. [15]), knowledge about their outcome beyond young adulthood is lacking. Therefore, we aimed to extend the findings of Bongers et al. [15], which are based on a previous wave of the current study, by examining the prediction of developmental trajectories in middle adulthood (i.e., from age 28 to 40 years).

Based on earlier findings, we expect that an elevated level of externalizing behavior in childhood has impact on the long-term outcome, in addition to the developmental course of externalizing behavior [5, 8, 11, 15, 22, 23]. Furthermore, we expect that different types of externalizing behavior (i.e., aggression, opposition, property violations, and status violations) are related to different adult outcomes [15, 16]. Finally, according to the fact that the oppositional and status violations type consist of more reactive and nondestructive behaviors, these types of problems are expected to develop into emotional problems. Because the property violations and aggression type consist of proactive, destructive behaviors, these types are expected to develop into behavior problems in adulthood [24, 25]. Because behavior problems of the status violations type have been found to increase with age [21], we expect that this type is associated with most adult problems.

Methods

Sample

In 1983, a sample of 2,600 children aged 4–16 years was randomly selected from the general population of the Dutch province of Zuid-Holland. A hundred children of each gender and age were drawn from the municipal registers listing all residents in the province A total of 2,447 parents of child participants could be reached, of whom 2,076 (84.8%) completed the Child Behavior Checklist (CBCL) on their child. Parents were interviewed at 2-year intervals until 1991 and the participants themselves were interviewed in 2006 and 2007 when they were 28–40 years old. We approached all participants from the original sample, except 23 who had died, 10 who were intellectually disabled, and 48 who had requested to be removed from the sample at an earlier stage of the study [26]. We reached 1,791 of the 1,995 participants, 452 refused and 1,339 respondents provided information for determining DSM-IV diagnoses, see Fig. 1. The response rate in the seventh data collection was 66% (1,339 of 2,043).

Fig. 1

Flowchart of the data collection between 1983 and 2007

To investigate selective attrition, we performed logistic regression analyses to look at associations between age, gender, socio-economic status (SES), and Total Problems Score of participants in 1983, and participation in 2006 and 2007. SES was scored on a six-step scale of parental occupation [27] with 1 = lowest SES. Total Problems Score was calculated by summing 118 of the specific item scores on emotional and behavioral problems in the CBCL. Although age, gender, and SES had significant influence on participation at follow-up, the differences were small. Participation was more likely when participants were women (51.1% for dropouts versus 53.7% for participants; OR = 1.33; CI 1.11–1.60; p < 0.002), if they were younger (mean age at baseline was 10.2 years for dropouts and 9.8 years for participants; OR = 0.97; CI 0.95–1.00; p < 0.026), and had a higher SES (3.4 for dropouts and 3.7 for participants; OR = 1.12; CI 1.06–1.19; p < 0.000). No influence on participation was found for Total Problems Score.

Measurements

Externalizing behavior trajectories

From 1983 to 1991 the CBCL was used to obtain standardized parent reports of children’s problem behaviors. Externalizing behavior trajectories were based on assessment with the CBCL. The CBCL is a rating scale intended for completion by parents of 4–18-year-old children; it contains 120 items covering behavioral or emotional problems that have occurred during the past 6 months. The items are scored on a three-point scale: 0 (not true), 1 (somewhat or sometimes true), and 2 (very true or often true). The reliability and validity of the CBCL [28] have been confirmed for the Dutch version [29].

We selected 21 externalizing behavior items of the CBCL, corresponding to items that Frick et al. [13] used for the classification of antisocial behavior into four types which are: aggression, opposition, property violations, and status violations (Table 1). The structure of the four types was confirmed with confirmatory factor analyses. The average goodness-of-fit index (GFI) across time 1–time 5 was 0.92 for males and 0.96 for females [21].

Table 1

Item description of the four externalizing behavior types

Frick cluster	Child behavior checklist item
Aggression	Cruelty, bullying, or meanness to others
	Gets in many fights
	Physically attacks people
	Threatens people
Opposition	Argues a lot
	Disobedient at home
	Disobedient at school
	Stubborn, sullen, or irritable
	Sulks a lot
	Teases a lot
	Temper tantrums or hot temper
Property violations	Cruel to animals
	Lying or cheating
	Sets fires
	Steals at home
	Steals outside the home
	Vandalism
Status violations	Runs away from home
	Swearing or obscene language
	Truancy, skips school
	Uses alcohol or drugs for not medical purposes

CBCL items to which the content showed a good match to the description provided by the authors of the types [13] that were clustered to form four types of externalizing behavior

Trajectories of externalizing behavior for ages 4–18 years were identified in a previous study on the Zuid-Holland data (see Fig. 2) [21]. A semi-parametric, group-based approach [20] was used to determine developmental trajectories of the four externalizing behavior types. The trajectories were based on the first five waves of this study. For every child, a trajectory was determined within each externalizing behavior type. Within the behavior types, the best possible number of groups with different developmental trajectories was estimated and selected using the Bayesian information criterion [20]. We used a Zero-Inflated Poisson (ZIP) distribution for estimating the trajectories. Estimation using a ZIP distribution addresses both non-normality and the abundance of zeros typically found in distributions of externalizing behavior [20, 21]. The largest probability for each individual indicated the trajectory that best matched to that individual’s behavior over time. With these probabilities, each child was assigned to the trajectory of each externalizing type that best described their individual developmental trajectory. Therefore, each child could be classified at the same time in, for example, a high-level trajectory for opposition and a low-level trajectory for aggression. There were equal amounts of younger and older children classified in each trajectory, since there were no age effects in the assignment of the individuals to the trajectories. The child’s trajectory group classifications were used in further analyses.

Fig. 2

Developmental trajectories in childhood antisocial behavior types. Group-based developmental trajectories of aggression, opposition, property violations, and status violations. The y axis represents the raw syndrome scores. (From Bongers et al. [21]; reprinted with permission of Blackwell Publishing.) Ado adolescence

Three trajectories were found for the externalizing behavior type aggression: a ‘near zero’ trajectory, a ‘low decreasers’ trajectory, and a ‘high decreasers’ trajectory. Six trajectories were found for the behavior type opposition: a ‘near zero’ trajectory, a ‘low decreasers’ trajectory, a ‘medium decreasers’ trajectory, an ‘adolescent increasers’ trajectory, a ‘high persisters’ trajectory, and a ‘high decreasers’ trajectory. Four trajectories were found for property violations: a ‘near zero’ trajectory, a ‘low decreasers’ trajectory, a ‘high persisters’ trajectory, and an ‘extremely high persisters’ trajectory. Because the ‘extremely high persisters’ group of property violations consisted of only two participants, this group was combined with the ‘high persisters’ group. In status violations, a ‘near zero’ trajectory, an ‘adolescent decreasers’ trajectory, a ‘medium increasers’ trajectory, and a ‘high increasers’ trajectory was found. The number of individuals within each trajectory can be found in Table 2.

Table 2

Number of participants in the developmental trajectories

Developmental trajectory	N	Percentage of total sample	Percentage males
Aggression
Near zero	1,473	71.0	41.7
Medium decreasers	444	21.4	65.3
High decreasers	159	7.7	70.4
Opposition
Near zero	148	7.1	43.9
Low decreasers	491	23.7	44.6
Medium decreasers	674	32.5	50.3
Adolescence increasers	125	6.0	41.6
High decreasers	503	24.2	53.5
High persisters	135	6.5	53.3
Property violations
Near zero	1,548	74.6	45.4
Low decreasers	421	20.3	56.3
High persisters	107	5.2	71.0
Status violations
Near zero	1,052	50.7	43.7
Adolescence increasers	485	23.4	46.8
Medium increasers	514	24.8	60.5
High increasers	25	1.2	72.0

Number of individuals within each trajectory, percentage of individuals within each trajectory of the total sample, and percentage of males within each trajectory of the total sample

The items of the CBCL can be scored on two general scales: internalizing behavior (i.e., anxiety and depression) and externalizing behavior (i.e., delinquent and aggressive behavior). In this study, we used internalizing and externalizing scores measured at time 1 in 1983.

To investigate selective attrition, all dropouts and participants were compared with respect to their 1983 scale scores, using analysis of variance (ANOVA) and adjusting for age and gender. No significant difference was found between participants with missing assessments and participants with assessments in all five waves, on any of the CBCL scales (see Bongers et al. [21] for further details about the analysis).

Composite International Diagnostic Interview

The computerized version of the Composite International Diagnostic Interview (CIDI; [30] and three sections of the Diagnostic Interview Schedule (DIS) for DSM-IV diagnoses [31] were used to obtain diagnoses of mental disorder in the 12 months prior to the interview (past year diagnoses). The CIDI and DIS are fully structured interviews to allow administration by lay interviewers and scoring of DSM-IV [32] by computer. Good reliability and validity have been reported for the CIDI [33]. Because information concerning disruptive disorders in adulthood (oppositional defiant, antisocial personality disorder, and ADHD) was lacking in this version of the CIDI, sections of the DIS covering these disorders were administered. Because the cell sizes for specific disorders were small for the majority of diagnoses, we constructed the following groupings of DSM-IV categories: (1) anxiety disorders, consisting of generalized anxiety disorder, obsessive–compulsive disorder, panic disorder, agoraphobia, social phobia, specific phobia, or any anxiety disorder; (2) mood disorders, consisting of major depressive episode, bipolar disorder, dysthymia, or any mood disorder; (3) substance abuse/dependence, consisting of alcohol abuse/dependence, drug abuse/dependence, or both; (4) disruptive disorders, consisting of oppositional defiant disorder, antisocial personality disorder, ADHD, attention deficit only, hyperactivity only, or any disruptive disorder; and (5) any disorder, consisting of any of the above disorders or other disorders such as bulimia nervosa, somatization, conversion, pain disorder, hypochondriasis, and brief psychotic disorder.

Statistical analyses

Logistic regression analyses

To investigate associations between childhood externalizing developmental trajectories in childhood and psychopathology in adulthood, we performed multiple logistic regression analyses for each externalizing behavior type separately. We tested whether associations existed between the trajectories in the four externalizing behavior types and DSM-IV disorders at follow-up. The regression analyses included gender, age, and SES at follow-up as covariates. Because the associations between the trajectories of externalizing behavior and adult disorders might be confounded by associations with internalizing and externalizing behavior, we added two more covariates. We added internalizing and externalizing scores assessed with the CBCL at time 1 to the regression analyses to adjust for their effects on the associations. In this way, we determined whether the trajectories predicted adult psychiatric disorders over and above comorbid general internalizing and externalizing behavior. For all models, we first determined whether there were interaction effects of sex or age with the separate trajectories. No significant interaction effects were found. The ‘near zero’ trajectory of each type was used as reference group in each regression analysis.

Results

In the multiple regression analyses, many associations were found between childhood externalizing developmental trajectories and adult disorders (Table 3). All four externalizing types predicted later disruptive disorders. Besides disruptive disorders, the oppositional type was also associated with anxiety disorders in adulthood. The trajectories in the status violations type also predicted substance abuse/dependence, anxiety, and mood disorder. Primarily high-level trajectories in the types predicted problems, but also medium-level trajectories were highly predictive.

Table 3

Associations between developmental trajectories of child externalizing problems and disorders in adulthood

Predictors	N	DSM-IV disorders at follow-up
		Any disorder N = 356OR (95% CI)	Disruptive disorder N = 121OR (95% CI)	Substance abuse/dependence N = 120OR (95% CI)	Anxiety disorder N = 183OR (95% CI)	Mood disorder N = 36OR (95% CI)
Aggression
High decreasers	82		2.4 (2.1–5.1)
Low decreasers	275
Near zero	982
Sex (male)			3.3 (2.1–5.1)	2.9 (1.9–4.5)	0.4 (0.3–0.6)	0.3 (0.2–0.8)
SES			0.9 (0.8–1.0)
General externalizing
General internalizing
Oppositional
High persisters	73	3.1 (1.3–7.5)	4.6 (1.2–17.7)		3.1 (1.1–9.6)
High decreasers	315	2.3 (1.2–4.3)
Ado increasers	89
Medium decreasers	426
Low decreasers	334
Near zero	102
Sex (male)			3.7 (2.4–5.7)	3.0 (1.9–4.5)	0.4 (0.3–0.6)	0.3 (0.1–0.7)
SES			0.9 (0.8–1.0)
General externalizing
General internalizing
Property violations
High persisters	55	2.3 (1.3–4.3)	3.8 (1.8–8.2)
Low decreasers	276	1.3 (1.0–1.8)	1.6 (1.0–2.6)
Near zero	1,008
Sex (male)			3.3 (2.2–5.1)	2.8 (1.9–4.3)	0.4 (0.3–0.6)	0.3 (0.1–0.7)
SES
General externalizing
General internalizing
Status violations
High increasers	15	3.8 (1.3–11.1)		11.7 (3.4–40.2)		7.1 (1.1–47.1)
Medium increasers	309	1.9 (1.4–2.6)	1.7 (1.1–2.8)	2.3 (1.4–3.8)	1.6 (1.1–2.5)
Ado increasers	320					2.8 (1.1–7.1)
Near zero	695
Sex (male)			3.3 (2.2–5.1)	2.7 (1.8–4.2)	0.4 (0.3–0.6)	0.3 (0.1–0.7)
SES
General externalizing
General internalizing

Odds ratios (95% confidence interval) are derived from multiple logistic regression analysis. Near zero groups were reference groups in the regression analyses. Only significant results are presented

Ado adolescence

Discussion

This study examined the relations between childhood trajectories of four distinctive types of externalizing behavior and DSM-IV disorders in adulthood in a longitudinal general-population sample that included males and females aged 4–16 years assessed at six time periods. All four types of externalizing behavior (i.e., aggression, opposition, property violations, and status violations) in childhood, showed associations with disruptive behavior in adulthood. Children displaying externalizing behavior of the oppositional type (e.g., arguing, disobedience, temper tantrums) also showed anxiety disorder in adulthood. Children in trajectories of the status violation type (e.g., runaway, truancy, drug, and alcohol use) showed primarily substance use, anxiety, and mood disorder in adulthood. Furthermore, we found that children who are in high-level externalizing behavior trajectories are most at risk to suffer from disorders in adulthood, that is, both internalizing and externalizing disorders. This 24-year follow-up study is unique in prospectively examining the adult outcomes of different developmental trajectories in four childhood types of externalizing behavior, in a large general-population sample of 1,399 children.

Consistent with results of previous longitudinal studies in the general population that investigated the long-term continuity of early externalizing behavior [5, 14, 34], we can conclude that children with externalizing behavior are at increased risk for adverse outcomes in adulthood. Moreover, even after 24 years, children in all subtypes of externalizing behavior are at increased risk to suffer from internalizing and externalizing adult disorders. In addition, our study emphasizes the need to distinguish between the subtypes of externalizing behavior because we found differences between the predictive values of the different types of externalizing behavior. Of the four types of externalizing behavior, aggression (mainly including physical aggression) showed the least associations with adult psychopathology, whereas opposition and property violations mainly predicted adult disruptive disorder.

The status violations subtype was the weakest predictor for later disruptive behavior. However, children with behavior problems of this type showed substance use, anxiety, and mood disorder in adulthood. In a study that investigated which subtypes of externalizing behavior accounted for substance use [16], it was also found that status violations predicts substance use in late adolescence. In our study, we found that even up to middle adulthood, strong associations were found between status violations and substance use. Studies that investigated the comorbidity between alcohol, drugs, and internalizing disorders reported that ‘self medication’ with alcohol or drugs was associated with an increased likelihood of anxiety disorders [35, 36]. This verifies our finding of anxiety and substance use disorder in adulthood being related to status violations. Furthermore, another possible explanation for our finding of associations between childhood externalizing behavior types and adult internalizing disorders could be that the status violations and oppositional type comprise behaviors that are more reactive, nondestructive, and affective behaviors, and entail negative emotionality (e.g., anger, runaway, rule breaking), in contrast to aggression and property violations types that primarily comprise proactive and violent behaviors that are offensive and instrumental (e.g., bullying, vandalism). Proactive and reactive aggressions are two distinct subtypes of externalizing behavior and they have been found to differ in adult outcome. Proactive individuals tend to bully and be very unemotional, whereas reactive individuals show impulsive, angry responses to aversive events, particularly perceived by interpersonal threat [24, 25]. In accordance with previous findings on reactive and proactive aggressive behavior, we found that children with more reactive, nondestructive externalizing problems (i.e., status violations and oppositional) suffer from later internalizing problems [25, 37].

Because externalizing behaviors are expected to change largely in level and growth during childhood and adolescence [5, 38], and are therefore best described from a developmental point of view [39], we explored outcomes of trajectories of behavior in the current study, taking into account the developmental change through childhood and adolescence. We used LCGA to analyze trajectories of externalizing behavior, because this method is well adapted for modeling growth of phenomena within a population in which population members are not following a common developmental process of growth or decline. Consequently, we were able to report unique associations between distinctive developmental trajectories within every externalizing behavior type and adult internalizing and externalizing outcomes.

In accordance with findings of previous studies that investigated development of externalizing behavior, we found that children in high-level externalizing trajectories are most likely to suffer from adult problems [5, 8, 11, 15, 22, 23]. Children in the most severe, high-level trajectory of opposition and property violations were almost four to five times more likely than children not displaying these problems to suffer from any disruptive behavior in adulthood. Findings of a study that investigated continuity of externalizing behavior up to the age of 32 show that externalizing individuals in a severe ‘life-course-persistent’ trajectory suffered from the most mental health problems [5]. In a review of conduct disorder and its outcomes in general population studies it was found that increasing severity of externalizing behavior was associated with an increasing risk of an emotional disorder in adulthood [11]. What this study adds to the literature is that we extend the above findings by confirming that high levels of externalizing behavior in childhood and adolescence are linked to poor outcomes in adulthood even up to age 40.

However, it should be noted that children in both low- and high-level trajectories of property violations showed persistence of externalizing behavior into adulthood in terms of having disruptive behavior in adulthood. This shows that children displaying behavior of the property violations type are at risk to suffer from adult problems, even if they develop through a low-level and decreasing trajectory during childhood and adolescence. Property violations comprise behaviors such as cruel to animals, fire setting, and vandalism. These behaviors are symptoms of both psychopathy and antisocial personality disorder [32, 40], which are both very serious diagnoses. Possibly, the separate symptoms in this property violations type are that severe and radical, that even children who show relatively few of the symptoms comprising this property violations type, thus who develop through a low-level in this type, suffer from disruptive disorder in adulthood.

Limitations

Our findings should be interpreted in light of two limitations. First, although we achieved a relatively high response rate in a 24-year follow-up, a considerable proportion of the original sample from 1983 did not participate in this follow-up. By interpreting our results, one should be aware of the fact that in longitudinal population based studies, high-risk people are the most difficult to keep included. Although selective attrition effects were small in this study, some children with the most severe externalizing behavior problems were not included. Therefore, results may not generalize to high-risk populations. Consequently, studies on high-risk children are essential to complete the present findings on the predictive value of developmental trajectories of externalizing behavior. Second, the results of this study may have been influenced by time dependent environmental covariates, such as economic growth, ethnic distributions, or family structures that we did not control for.

Conclusions

Our study shows a relation between child to adolescent externalizing behavior and adult psychopathology, even over a 24 years time-interval. We can conclude that an elevated level of externalizing behavior in childhood has impact on the long-term outcome, regardless of the developmental course of externalizing behavior. Therefore, intervention and prevention should focus on individuals that show severe externalizing problems at any point in childhood or adolescence. Furthermore, we can conclude that different types of externalizing behavior (i.e., aggression, opposition, property violations, and status violations) are related to different adult outcomes, and it is therefore advisable to treat them separately. Mental health professionals working with children and adolescents with externalizing behavior should anticipate different developmental trajectories through life. Because children and adolescents with externalizing behavior of the status violations subtype were most likely to be affected in adulthood, we recommend that prevention and intervention should focus on children and adolescents showing behavior of this type such as substance abuse, truancy, and runaway.