Literature DB >> 20935481

NFAT transcription factors, the potion mediating "Dr. Jekill-Mr. Hyde" transformation of the TGFβ pathway in cancer cells.

Martin E Fernandez-Zapico, Volker Ellenrieder.   

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Year:  2010        PMID： 20935481      PMCID： PMC3005288          DOI： 10.4161/cc.9.19.13413

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  11 in total

1.  E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression.

Authors:  Chang-Rung Chen; Yibin Kang; Peter M Siegel; Joan Massagué
Journal:  Cell       Date:  2002-07-12       Impact factor: 41.582

Review 2.  Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer.

Authors:  Peter M Siegel; Joan Massagué
Journal:  Nat Rev Cancer       Date:  2003-11       Impact factor: 60.716

Review 3.  Smad transcription factors.

Authors:  Joan Massagué; Joan Seoane; David Wotton
Journal:  Genes Dev       Date:  2005-12-01       Impact factor: 11.361

Review 4.  Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer.

Authors:  Brian Bierie; Harold L Moses
Journal:  Nat Rev Cancer       Date:  2006-07       Impact factor: 60.716

5.  Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.

Authors:  Garima Singh; Shiv K Singh; Alexander König; Kristina Reutlinger; Monica D Nye; Tillman Adhikary; Martin Eilers; Thomas M Gress; Martin E Fernandez-Zapico; Volker Ellenrieder
Journal:  J Biol Chem       Date:  2010-06-01       Impact factor: 5.157

6.  Repression of p15INK4b expression by Myc through association with Miz-1.

Authors:  P Staller; K Peukert; A Kiermaier; J Seoane; J Lukas; H Karsunky; T Möröy; J Bartek; J Massagué; F Hänel; M Eilers
Journal:  Nat Cell Biol       Date:  2001-04       Impact factor: 28.824

Review 7.  TGFbeta in Cancer.

Authors:  Joan Massagué
Journal:  Cell       Date:  2008-07-25       Impact factor: 41.582

8.  NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.

Authors:  Alexander Köenig; Thomas Linhart; Katrin Schlengemann; Kristina Reutlinger; Jessica Wegele; Guido Adler; Garima Singh; Leonie Hofmann; Steffen Kunsch; Thomas Büch; Eva Schäfer; Thomas M Gress; Martin E Fernandez-Zapico; Volker Ellenrieder
Journal:  Gastroenterology       Date:  2009-11-06       Impact factor: 22.682

Review 9.  NFAT proteins: emerging roles in cancer progression.

Authors:  Maria Mancini; Alex Toker
Journal:  Nat Rev Cancer       Date:  2009-11       Impact factor: 60.716

Review 10.  TGFbeta regulated gene expression by Smads and Sp1/KLF-like transcription factors in cancer.

Authors:  Volker Ellenrieder
Journal:  Anticancer Res       Date:  2008 May-Jun       Impact factor: 2.480
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  6 in total

Review 1.  NFAT as cancer target: mission possible?

Authors:  Jiang-Jiang Qin; Subhasree Nag; Wei Wang; Jianwei Zhou; Wei-Dong Zhang; Hui Wang; Ruiwen Zhang
Journal:  Biochim Biophys Acta       Date:  2014-07-26

2.  Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway.

Authors:  Miriam B F Werneck; Eugênio Hottz; Patricia T Bozza; João P B Viola
Journal:  Cell Cycle       Date:  2012-09-19       Impact factor: 4.534

3.  WNT5A-NFAT signaling mediates resistance to apoptosis in pancreatic cancer.

Authors:  Heidi Griesmann; Stefanie Ripka; Moritz Pralle; Volker Ellenrieder; Sandra Baumgart; Malte Buchholz; Christian Pilarsky; Daniela Aust; Thomas M Gress; Patrick Michl
Journal:  Neoplasia       Date:  2013-01       Impact factor: 5.715

Review 4.  Decorin as a multivalent therapeutic agent against cancer.

Authors:  Thomas Neill; Liliana Schaefer; Renato V Iozzo
Journal:  Adv Drug Deliv Rev       Date:  2015-10-30       Impact factor: 15.470

5.  MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3.

Authors:  Chunyou Wang; Pian Liu; Heshui Wu; Pengfei Cui; Yongfeng Li; Yao Liu; Zhiqiang Liu; Shanmiao Gou
Journal:  Oncotarget       Date:  2016-03-22

6.  Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression.

Authors:  Johanna Eriksson; Vadim Le Joncour; Pirjo Nummela; Tiina Jahkola; Susanna Virolainen; Pirjo Laakkonen; Olli Saksela; Erkki Hölttä
Journal:  Oncotarget       Date:  2016-03-22
  6 in total

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