Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Functions of B56-containing PP2As in major developmental and cancer signaling pathways.

Literature DB >> 20934435

Functions of B56-containing PP2As in major developmental and cancer signaling pathways.

Abstract

Members of the B'/B56/PR61 family regulatory subunits of PP2A determine the subcellular localization, substrate specificity, and catalytic activity of PP2A in a wide range of biological processes. Here, we summarize the structure and intracellular localization of B56-containing PP2As and review functions of B56-containing PP2As in several major developmental/cancer signaling pathways.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2010 PMID： 20934435 PMCID： PMC2993835 DOI： 10.1016/j.lfs.2010.10.003

Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037

116 in total

Review 1. From promiscuity to precision: protein phosphatases get a makeover.

Authors: David M Virshup; Shirish Shenolikar
Journal: Mol Cell Date: 2009-03-13 Impact factor: 17.970

Review 2. Wnt/beta-catenin signaling: components, mechanisms, and diseases.

Authors: Bryan T MacDonald; Keiko Tamai; Xi He
Journal: Dev Cell Date: 2009-07 Impact factor: 12.270

3. Recent natural selection identifies a genetic variant in a regulatory subunit of protein phosphatase 2A that associates with altered cancer risk and survival.

Authors: Lukasz F Grochola; Alexei Vazquez; Elisabeth E Bond; Peter Würl; Helge Taubert; Thomas H Müller; Arnold J Levine; Gareth L Bond
Journal: Clin Cancer Res Date: 2009-09-22 Impact factor: 12.531

4. Structure and function of the PP2A-shugoshin interaction.

Authors: Zheng Xu; Bulent Cetin; Martin Anger; Uhn Soo Cho; Wolfgang Helmhart; Kim Nasmyth; Wenqing Xu
Journal: Mol Cell Date: 2009-08-28 Impact factor: 17.970

Review 5. Cytoplasmic functions of the tumour suppressor p53.

Authors: Douglas R Green; Guido Kroemer
Journal: Nature Date: 2009-04-30 Impact factor: 49.962

Review 6. Serine/threonine phosphatases: mechanism through structure.

Authors: Yigong Shi
Journal: Cell Date: 2009-10-30 Impact factor: 41.582

7. The 48-kDa alternative translation isoform of PP2A:B56epsilon is required for Wnt signaling during midbrain-hindbrain boundary formation.

Authors: Zhigang Jin; Jianli Shi; Amit Saraf; Wenyan Mei; Guo-Zhang Zhu; Stefan Strack; Jing Yang
Journal: J Biol Chem Date: 2009-01-07 Impact factor: 5.157

8. A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation.

Authors: Srivatsan Padmanabhan; Arnab Mukhopadhyay; Sri Devi Narasimhan; Gregory Tesz; Michael P Czech; Heidi A Tissenbaum
Journal: Cell Date: 2009-02-26 Impact factor: 41.582

Review 9. The mitochondrial p53 pathway.

Authors: Angelina V Vaseva; Ute M Moll
Journal: Biochim Biophys Acta Date: 2008-10-25

Review 10. Making a grade: Sonic Hedgehog signalling and the control of neural cell fate.

Authors: James Briscoe
Journal: EMBO J Date: 2009-02-05 Impact factor: 11.598

29 in total

1. Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation.

Authors: Yoko Naito; Norikazu Yabuta; Jun Sato; Shouichi Ohno; Muneki Sakata; Takashi Kasama; Masahito Ikawa; Hiroshi Nojima
Journal: Cell Cycle Date: 2013-05-08 Impact factor: 4.534

2. Retroviral cyclin enhances cyclin-dependent kinase-8 activity.

Authors: Joel Rovnak; Connie D Brewster; Sandra L Quackenbush
Journal: J Virol Date: 2012-02-29 Impact factor: 5.103

Review 3. AKAP phosphatase complexes in the heart.

Authors: John M Redden; Kimberly L Dodge-Kafka
Journal: J Cardiovasc Pharmacol Date: 2011-10 Impact factor: 3.105

4. Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta.

Authors: Justin V Louis; Ellen Martens; Peter Borghgraef; Caroline Lambrecht; Ward Sents; Sari Longin; Karen Zwaenepoel; Robert Pijnenborg; Isabelle Landrieu; Guy Lippens; Birgit Ledermann; Jürgen Götz; Fred Van Leuven; Jozef Goris; Veerle Janssens
Journal: Proc Natl Acad Sci U S A Date: 2011-04-11 Impact factor: 11.205

5. The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.

Authors: Zhigang Jin; Wenyan Mei; Stefan Strack; Jianhang Jia; Jing Yang
Journal: J Biol Chem Date: 2011-08-30 Impact factor: 5.157

6. B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.

Authors: Gunnar Houge; Dorien Haesen; Lisenka E L M Vissers; Sarju Mehta; Michael J Parker; Michael Wright; Julie Vogt; Shane McKee; John L Tolmie; Nuno Cordeiro; Tjitske Kleefstra; Marjolein H Willemsen; Margot R F Reijnders; Siren Berland; Eli Hayman; Eli Lahat; Eva H Brilstra; Koen L I van Gassen; Evelien Zonneveld-Huijssoon; Charlotte I de Bie; Alexander Hoischen; Evan E Eichler; Rita Holdhus; Vidar M Steen; Stein Ove Døskeland; Matthew E Hurles; David R FitzPatrick; Veerle Janssens
Journal: J Clin Invest Date: 2015-07-13 Impact factor: 14.808

7. ELAS1-mediated inhibition of the cyclin G1-B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53.

Authors: S Ohno; Y Naito; S Mukai; N Yabuta; H Nojima
Journal: Oncogene Date: 2015-04-27 Impact factor: 9.867