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Literature DB >> 20932927

Composition, assembly, and maintenance of excitable membrane domains in myelinated axons.

Abstract

Neurons have many specialized membrane domains with diverse functions responsible for receiving, integrating, and transmitting electrical signals between cells in a circuit. Both the locations and protein compositions of these domains defines their functions. In axons, two of the most important membrane domains are the axon initial segment and the nodes of Ranvier. Proper assembly and maintenance of these domains is necessary for action potential generation and propagation, and the overall function of the neuron.

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Year: 2010 PMID： 20932927 PMCID： PMC3037441 DOI： 10.1016/j.semcdb.2010.09.010

Source DB: PubMed Journal: Semin Cell Dev Biol ISSN： 1084-9521 Impact factor: 7.727

85 in total

1. Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve.

Authors: M E Boyle; E O Berglund; K K Murai; L Weber; E Peles; B Ranscht
Journal: Neuron Date: 2001-05 Impact factor: 17.173

2. Early events in node of Ranvier formation during myelination and remyelination in the PNS.

Authors: Dorothy P Schafer; Andrew W Custer; Peter Shrager; Matthew N Rasband
Journal: Neuron Glia Biol Date: 2006-05

3. Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.

Authors: Yasuhiro Ogawa; Dorothy P Schafer; Ido Horresh; Vered Bar; Kimberly Hales; Yang Yang; Keiichiro Susuki; Elior Peles; Michael C Stankewich; Matthew N Rasband
Journal: J Neurosci Date: 2006-05-10 Impact factor: 6.167

4. Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy.

Authors: Maarten H P Kole; Johannes J Letzkus; Greg J Stuart
Journal: Neuron Date: 2007-08-16 Impact factor: 17.173

5. Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments.

Authors: Amandine Duflocq; Barbara Le Bras; Erika Bullier; François Couraud; Marc Davenne
Journal: Mol Cell Neurosci Date: 2008-06-24 Impact factor: 4.314

6. Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns.

Authors: I Vabnick; J S Trimmer; T L Schwarz; S R Levinson; D Risal; P Shrager
Journal: J Neurosci Date: 1999-01-15 Impact factor: 6.167

7. Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2.

Authors: Kevin A Strauss; Erik G Puffenberger; Matthew J Huentelman; Steven Gottlieb; Seth E Dobrin; Jennifer M Parod; Dietrich A Stephan; D Holmes Morton
Journal: N Engl J Med Date: 2006-03-30 Impact factor: 91.245

8. Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.

Authors: P Weber; U Bartsch; M N Rasband; R Czaniera; Y Lang; H Bluethmann; R U Margolis; S R Levinson; P Shrager; D Montag; M Schachner
Journal: J Neurosci Date: 1999-06-01 Impact factor: 6.167

Review 9. Molecular mechanisms of node of Ranvier formation.

Authors: Keiichiro Susuki; Matthew N Rasband
Journal: Curr Opin Cell Biol Date: 2008-11-01 Impact factor: 8.382

10. KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.

Authors: J R Schwarz; G Glassmeier; E C Cooper; T-C Kao; H Nodera; D Tabuena; R Kaji; H Bostock
Journal: J Physiol Date: 2006-03-09 Impact factor: 5.182

24 in total

Review 1. The back and forth of axonal injury and repair after stroke.

Authors: Jason D Hinman
Journal: Curr Opin Neurol Date: 2014-12 Impact factor: 5.710

2. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels.

Authors: Edward Glasscock; Jing Qian; Matthew J Kole; Jeffrey L Noebels
Journal: J Physiol Date: 2012-05-28 Impact factor: 5.182

Review 3. Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity.

Authors: James S Trimmer
Journal: Neuron Date: 2015-01-21 Impact factor: 17.173

Composition, assembly, and maintenance of excitable membrane domains in myelinated axons.

1. Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve.

2. Early events in node of Ranvier formation during myelination and remyelination in the PNS.

3. Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.

4. Axon initial segment Kv1 channels control axonal action potential waveform and synaptic efficacy.

5. Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments.

6. Dynamic potassium channel distributions during axonal development prevent aberrant firing patterns.

7. Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2.

8. Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS.

Review 9. Molecular mechanisms of node of Ranvier formation.

10. KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier.

Review 1. The back and forth of axonal injury and repair after stroke.

2. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels.

Review 3. Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity.

Review 4. Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment.

Review 5. Autoimmune antigenic targets at the node of Ranvier in demyelinating disorders.

Review 6. The making of a node: a co-production of neurons and glia.

Review 7. The axon-glia unit in white matter stroke: mechanisms of damage and recovery.

8. Mild traumatic brain injury in the mouse induces axotomy primarily within the axon initial segment.

9. Evolution of peripheral nerve function in humans: novel insights from motor nerve excitability.

Review 10. Role of calpains in the injury-induced dysfunction and degeneration of the mammalian axon.