OBJECTIVE: Although the prevalence of dementia in remote living Aboriginal Australians is one of the highest in the world, the factors associated with dementia in this population are yet to be examined. This study was designed to determine the demographic, lifestyle and clinical factors associated with dementia in Aboriginal Australians living in the Kimberley region of Western Australia. METHOD: A total of 363 Aboriginal Australians aged over 45 years from the Kimberley region were selected by semi-purposeful sampling. The factors analysed for association with dementia were age, sex, education, smoking, chewing tobacco, alcohol, head injury, heart disease, hypertension, diabetes, previous stroke, epilepsy, falls, mobility, incontinence, urinary problems, vision and hearing. This exposure data was collected from participants' and informants' reports using the Kimberley Indigenous Cognitive Assessment and specialist review, and medical records. RESULTS: Factors associated with dementia included older age, male gender (OR 3.1, 95%CI 1.4, 6.8) and no formal education (OR 2.7, 95%CI 1.1, 6.7) and after adjusting for age, sex and education, dementia was associated with current smoking (OR 4.5, 95%CI 1.1, 18.6), previous stroke (OR 17.9, 95%CI 5.9, 49.7), epilepsy (OR 33.5, 95%CI 4.8, 232.3), head injury (OR 4.0, 95%CI 1.7, 9.4), and poor mobility, incontinence and falls. CONCLUSIONS: Interventions aimed at better management or prevention of the modifiable factors identified could reduce dementia risk in Aboriginal populations.
OBJECTIVE: Although the prevalence of dementia in remote living Aboriginal Australians is one of the highest in the world, the factors associated with dementia in this population are yet to be examined. This study was designed to determine the demographic, lifestyle and clinical factors associated with dementia in Aboriginal Australians living in the Kimberley region of Western Australia. METHOD: A total of 363 Aboriginal Australians aged over 45 years from the Kimberley region were selected by semi-purposeful sampling. The factors analysed for association with dementia were age, sex, education, smoking, chewing tobacco, alcohol, head injury, heart disease, hypertension, diabetes, previous stroke, epilepsy, falls, mobility, incontinence, urinary problems, vision and hearing. This exposure data was collected from participants' and informants' reports using the Kimberley Indigenous Cognitive Assessment and specialist review, and medical records. RESULTS: Factors associated with dementia included older age, male gender (OR 3.1, 95%CI 1.4, 6.8) and no formal education (OR 2.7, 95%CI 1.1, 6.7) and after adjusting for age, sex and education, dementia was associated with current smoking (OR 4.5, 95%CI 1.1, 18.6), previous stroke (OR 17.9, 95%CI 5.9, 49.7), epilepsy (OR 33.5, 95%CI 4.8, 232.3), head injury (OR 4.0, 95%CI 1.7, 9.4), and poor mobility, incontinence and falls. CONCLUSIONS: Interventions aimed at better management or prevention of the modifiable factors identified could reduce dementia risk in Aboriginal populations.
Authors: David C Perry; Virginia E Sturm; Matthew J Peterson; Carl F Pieper; Thomas Bullock; Bradley F Boeve; Bruce L Miller; Kevin M Guskiewicz; Mitchel S Berger; Joel H Kramer; Kathleen A Welsh-Bohmer Journal: J Neurosurg Date: 2015-08-28 Impact factor: 5.115
Authors: Fintan Thompson; Sarah Russell; Rachel Quigley; Betty Sagigi; Sean Taylor; Malcolm McDonald; Sandy Campbell; Adrian Esterman; Linton R Harriss; Gavin Miller; Edward Strivens; Robyn McDermott Journal: Lancet Reg Health West Pac Date: 2022-07-06
Authors: Hannah Derrig; Louise M Lavrencic; Gerald A Broe; Brian Draper; Robert G Cumming; Gail Garvey; Thi Yen Hill; Gail Daylight; Simon Chalkley; Holly Mack; Danielle Lasschuit; Kim Delbaere; Kylie Radford Journal: Alzheimers Dement (N Y) Date: 2020-08-24
Authors: Kylie Radford; Louise M Lavrencic; Kim Delbaere; Brian Draper; Robert Cumming; Gail Daylight; Holly A Mack; Simon Chalkley; Hayley Bennett; Gail Garvey; Thi Yen Hill; Danielle Lasschuit; Gerald A Broe Journal: J Alzheimers Dis Date: 2019 Impact factor: 4.472
Authors: Fintan Thompson; Sarah G Russell; Linton R Harriss; Adrian Esterman; Sean Taylor; Rachel Quigley; Edward Strivens; Robyn McDermott Journal: Front Public Health Date: 2022-02-16
Authors: Letizia Maria Atim; Mark Mohan Kaggwa; Mohammed A Mamun; Scholastic Ashaba; Samuel Maling Journal: Clin Interv Aging Date: 2021-07-22 Impact factor: 4.458