Literature DB >> 20929258

Psiguadials A and B, two novel meroterpenoids with unusual skeletons from the leaves of Psidium guajava.

Meng Shao1, Ying Wang, Zhong Liu, Dong-Mei Zhang, Hui-Hui Cao, Ren-Wang Jiang, Chun-Lin Fan, Xiao-Qi Zhang, He-Ru Chen, Xin-Sheng Yao, Wen-Cai Ye.   

Abstract

Psiguadials A (1) and B (2), two novel sesquiterpenoid-diphenylmethane meroterpenoids with unusual skeletons, along with a pair of known epimers, psidial A (3) and guajadial (4), were isolated from the leaves of Psidium guajava. Their structures with absolute configurations were elucidated by means of NMR, X-ray diffraction, and quantum chemical CD calculation. Compounds 1, 2, and 4 exhibited potent inhibitory effects on the growth of human hepatoma cells.

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Year:  2010        PMID： 20929258     DOI： 10.1021/ol102179u

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

Review 1.  Recent advances in the synthesis of gem-dimethylcyclobutane natural products.

Authors:  Erin N Hancock; Johannes M Wiest; M Kevin Brown
Journal:  Nat Prod Rep       Date:  2019-10-16       Impact factor: 13.423

2.  Eucalyptals D and E, new cytotoxic phloroglucinols from the fruits of Eucalyptus globulus and assignment of absolute configuration.

Authors:  Ji Wang; Wen-Zhu Zhai; Yike Zou; Jing-Jing Zhu; Juan Xiong; Yun Zhao; Guo-Xun Yang; Hui Fan; Mark T Hamann; Gang Xia; Jin-Feng Hu
Journal:  Tetrahedron Lett       Date:  2012-03-25       Impact factor: 2.415

Review 3.  Biological activities of meroterpenoids isolated from different sources.

Authors:  Neeraj Kumar Fuloria; Radhika K Raheja; Kaushal H Shah; Manisha J Oza; Yogesh A Kulkarni; Vetriselvan Subramaniyan; Mahendran Sekar; Shivkanya Fuloria
Journal:  Front Pharmacol       Date:  2022-09-19       Impact factor: 5.988

4.  Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B.

Authors:  Lauren M Chapman; Jordan C Beck; Caitlin R Lacker; Linglin Wu; Sarah E Reisman
Journal:  J Org Chem       Date:  2018-05-18       Impact factor: 4.354

5.  Iridium-Catalyzed Enantioselective Allylic Substitution of Enol Silanes from Vinylogous Esters and Amides.

Authors:  Ming Chen; John F Hartwig
Journal:  J Am Chem Soc       Date:  2015-10-23       Impact factor: 15.419

Review 6.  An invocation for computational evaluation of isomerization transforms: cationic skeletal reorganizations as a case study.

Authors:  Alexander W Schuppe; Yannan Liu; Timothy R Newhouse
Journal:  Nat Prod Rep       Date:  2020-09-15       Impact factor: 13.423

Review 7.  Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis.

Authors:  Trevor N Purdy; Bradley S Moore; April L Lukowski
Journal:  J Nat Prod       Date:  2022-02-02       Impact factor: 4.803

8.  Quantification and Localization of Formylated Phloroglucinol Compounds (FPCs) in Eucalyptus Species.

Authors:  Bruna Marques Dos Santos; Juliane F S Zibrandtsen; Disan Gunbilig; Mette Sørensen; Federico Cozzi; Berin A Boughton; Allison Maree Heskes; Elizabeth Heather Jakobsen Neilson
Journal:  Front Plant Sci       Date:  2019-02-26       Impact factor: 5.753

9.  Psiguajadials A-K: Unusual Psidium Meroterpenoids as Phosphodiesterase-4 Inhibitors from the Leaves of Psidium guajava.

Authors:  Gui-Hua Tang; Zhen Dong; Yan-Qiong Guo; Zhong-Bin Cheng; Chu-Jun Zhou; Sheng Yin
Journal:  Sci Rep       Date:  2017-04-21       Impact factor: 4.379
  9 in total

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