Literature DB >> 20926712

Evaluation of time to detection of Mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials.

Marc Weiner1, Thomas J Prihoda, William Burman, John L Johnson, Stefan Goldberg, Nesri Padayatchi, Paula Duran, Melissa Engle, Grace Muzanye, Roy D Mugerwa, A Willem Sturm.   

Abstract

Time to detection of Mycobacterium tuberculosis in broth culture was examined for utility as a treatment efficacy end point. Of 146 patients in a phase IIB trial, a decreased mean time to detection was found in 5 with treatment failure. Time to detection in an analysis-of-covariance model was associated with lung cavities, less intensive treatment, and differences in the bactericidal effects of treatment regimens.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20926712      PMCID： PMC3008491          DOI： 10.1128/JCM.00757-10

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  15 in total

1.  American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis.

Authors:  Henry M Blumberg; William J Burman; Richard E Chaisson; Charles L Daley; Sue C Etkind; Lloyd N Friedman; Paula Fujiwara; Malgosia Grzemska; Philip C Hopewell; Michael D Iseman; Robert M Jasmer; Venkatarama Koppaka; Richard I Menzies; Richard J O'Brien; Randall R Reves; Lee B Reichman; Patricia M Simone; Jeffrey R Starke; Andrew A Vernon
Journal:  Am J Respir Crit Care Med       Date:  2003-02-15       Impact factor: 21.405

2.  A nested case-control study on treatment-related risk factors for early relapse of tuberculosis.

Authors:  Kwok C Chang; Chi C Leung; Wing W Yew; Suzanne C Ho; Cheuk M Tam
Journal:  Am J Respir Crit Care Med       Date:  2004-09-16       Impact factor: 21.405

Review 3.  Dosing schedules of 6-month regimens and relapse for pulmonary tuberculosis.

Authors:  Kwok C Chang; Chi C Leung; Wing W Yew; Shiu L Chan; Cheuk M Tam
Journal:  Am J Respir Crit Care Med       Date:  2006-08-14       Impact factor: 21.405

4.  Time to detection of Mycobacterium tuberculosis in sputum culture correlates with outcome in patients receiving treatment for pulmonary tuberculosis.

Authors:  M D Epstein; N W Schluger; A L Davidow; S Bonk; W N Rom; B Hanna
Journal:  Chest       Date:  1998-02       Impact factor: 9.410

5.  [Short term chemotherapy of tuberculosis. Factors affecting relapse following short term chemotherapy].

Authors:  V R Aber; A J Nunn
Journal:  Bull Int Union Tuberc       Date:  1978-12

6.  Assessment of new sterilizing drugs for treating pulmonary tuberculosis by culture at 2 months.

Authors:  D A Mitchison
Journal:  Am Rev Respir Dis       Date:  1993-04

7.  The early bactericidal activity of drugs in patients with pulmonary tuberculosis.

Authors:  A Jindani; V R Aber; E A Edwards; D A Mitchison
Journal:  Am Rev Respir Dis       Date:  1980-06

8.  Moxifloxacin versus ethambutol in the first 2 months of treatment for pulmonary tuberculosis.

Authors:  William J Burman; Stefan Goldberg; John L Johnson; Grace Muzanye; Melissa Engle; Ann W Mosher; Shurjeel Choudhri; Charles L Daley; Sonal S Munsiff; Zhen Zhao; Andrew Vernon; Richard E Chaisson
Journal:  Am J Respir Crit Care Med       Date:  2006-05-04       Impact factor: 21.405

9.  Quantitative sputum bacillary load during rifampin-containing short course chemotherapy in human immunodeficiency virus-infected and non-infected adults with pulmonary tuberculosis.

Authors:  M L Joloba; J L Johnson; A Namale; A Morrissey; A E Assegghai; R D Mugerwa; J J Ellner; K D Eisenach
Journal:  Int J Tuberc Lung Dis       Date:  2000-06       Impact factor: 2.373

10.  Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis.

Authors:  Susan E Dorman; John L Johnson; Stefan Goldberg; Grace Muzanye; Nesri Padayatchi; Lorna Bozeman; Charles M Heilig; John Bernardo; Shurjeel Choudhri; Jacques H Grosset; Elizabeth Guy; Priya Guyadeen; Maria Corazon Leus; Gina Maltas; Dick Menzies; Eric L Nuermberger; Margarita Villarino; Andrew Vernon; Richard E Chaisson
Journal:  Am J Respir Crit Care Med       Date:  2009-04-30       Impact factor: 21.405
View more
  8 in total

1.  Pretreatment time to detection of Mycobacterium tuberculosis in liquid culture is associated with relapse after therapy.

Authors:  Charles M Bark; Bonnie A Thiel; John L Johnson
Journal:  J Clin Microbiol       Date:  2011-11-23       Impact factor: 5.948

2.  Sputum volume predicts sputum mycobacterial load during the first 2 weeks of antituberculosis treatment.

Authors:  Miriam N Karinja; Tonya M Esterhuizen; Sven O Friedrich; Andreas H Diacon
Journal:  J Clin Microbiol       Date:  2014-12-31       Impact factor: 5.948

3.  Time to detection of Mycobacterium tuberculosis as an alternative to quantitative cultures.

Authors:  C M Bark; A Okwera; M L Joloba; B A Thiel; J G Nakibali; S M Debanne; W H Boom; K D Eisenach; J L Johnson
Journal:  Tuberculosis (Edinb)       Date:  2011-02-25       Impact factor: 3.131

4.  A time-to-event pharmacodynamic model describing treatment response in patients with pulmonary tuberculosis using days to positivity in automated liquid mycobacterial culture.

Authors:  Emmanuel Chigutsa; Kashyap Patel; Paolo Denti; Marianne Visser; Gary Maartens; Carl M J Kirkpatrick; Helen McIlleron; Mats O Karlsson
Journal:  Antimicrob Agents Chemother       Date:  2012-11-26       Impact factor: 5.191

5.  Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis.

Authors:  Derek J Sloan; Henry C Mwandumba; Natalie J Garton; Saye H Khoo; Anthony E Butterworth; Theresa J Allain; Robert S Heyderman; Elizabeth L Corbett; Mike R Barer; Geraint R Davies
Journal:  Clin Infect Dis       Date:  2015-03-16       Impact factor: 9.079

6.  Serial image analysis of Mycobacterium tuberculosis colony growth reveals a persistent subpopulation in sputum during treatment of pulmonary TB.

Authors:  David A Barr; Mercy Kamdolozi; Yo Nishihara; Victor Ndhlovu; Margaret Khonga; Geraint R Davies; Derek J Sloan
Journal:  Tuberculosis (Edinb)       Date:  2016-03-23       Impact factor: 3.131

7.  Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial.

Authors:  Ray Y Chen; Laura E Via; Lori E Dodd; Gerhard Walzl; Stephanus T Malherbe; André G Loxton; Rodney Dawson; Robert J Wilkinson; Friedrich Thienemann; Michele Tameris; Mark Hatherill; Andreas H Diacon; Xin Liu; Jin Xing; Xiaowei Jin; Zhenya Ma; Shouguo Pan; Guolong Zhang; Qian Gao; Qi Jiang; Hong Zhu; Lili Liang; Hongfei Duan; Taeksun Song; David Alland; Michael Tartakovsky; Alex Rosenthal; Christopher Whalen; Michael Duvenhage; Ying Cai; Lisa C Goldfeder; Kriti Arora; Bronwyn Smith; Jill Winter; Clifton E Barry Iii
Journal:  Gates Open Res       Date:  2017-11-06

8.  Longitudinal Model-Based Biomarker Analysis of Exposure-Response Relationships in Adults with Pulmonary Tuberculosis.

Authors:  Andrew D Gewitz; Belén P Solans; William R Mac Kenzie; Chad Heilig; William C Whitworth; John L Johnson; Pheona Nsubuga; Susan Dorman; Marc Weiner; Radojka M Savic
Journal:  Antimicrob Agents Chemother       Date:  2021-07-12       Impact factor: 5.191
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.