Literature DB >> 20922768

High frequency of cognitive dysfunction before stroke among older people.

C Gutiérrez Pérez1, M Sävborg, U Påhlman, M Cederfeldt, E Knopp, A Nordlund, R Astrand, A Wallin, K Fröjd, H Wijk, E Tarkowski.   

Abstract

OBJECTIVES: We examined cognitive functions before and in acute phase of stroke studying frequency and profile of cognitive impairment and relationships between cognitive status.
METHODS: Seventy-four patients with early phase after stroke and 49 healthy controls were included and examined using the Mini-Mental State Examination (MMSE) and a battery of neuropsychological tests. Cognitive status before stroke-onset was investigated using Cognitive Impairment Questionnaire.
RESULTS: Cognitive impairments were present in 96% of patients after stroke onset using the battery of neuropsychological tests and in 39% of patients using the MMSE, but in only 9% of controls. Seventy-six percent exhibited reduced executive function and 75% reduced psychomotor tempo. Cognitive dysfunction was present in 52% before stroke onset without any impact on the frequency of impairment in the various cognitive areas in early phase after stroke.
CONCLUSIONS: Cognitive impairment is frequent before the onset of stroke among older people and may partially explain the very high frequency of cognitive impairment observed after stroke onset.
Copyright © 2010 John Wiley & Sons, Ltd.

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Year:  2010        PMID: 20922768     DOI: 10.1002/gps.2573

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN: 0885-6230            Impact factor:   3.485


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