Literature DB >> 209185

6beta-[N,N-Bis(2-chloroethyl)amino]-17-(cyclopropylmethyl)-4,5alpha-epoxy-3,14-dihydroxymorphinan(chlornaltrexamine) a potent opioid receptor alkylating agent with ultralong narcotic antagonist actitivty.

P S Portoghese, D L Larson, J B Jiang, A E Takemori, T P Caruso.   

Abstract

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Year:  1978        PMID： 209185     DOI： 10.1021/jm00205a002

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  7 in total

1.  Reversible or irreversible modification of [3H]PAF binding on rabbit platelet membranes differentiates various PAF receptor antagonists.

Authors:  M T Domingo; F Piro; C Broquet; E Auclair; P E Chabrier; P Braquet
Journal:  Lipids       Date:  1992-08       Impact factor: 1.880

2.  Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance.

Authors:  Jay P McLaughlin; Lisa C Myers; Paul E Zarek; Marc G Caron; Robert J Lefkowitz; Traci A Czyzyk; John E Pintar; Charles Chavkin
Journal:  J Biol Chem       Date:  2003-11-03       Impact factor: 5.157

3.  Affinity labeling mu opioid receptors with novel radioligands.

Authors:  Ke Yang; Amy Zuckerman; Gavril W Pasternak
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046

Review 4.  Dynorphin--still an extraordinarily potent opioid peptide.

Authors:  Charles Chavkin
Journal:  Mol Pharmacol       Date:  2012-11-14       Impact factor: 4.436

Review 5.  Dynorphin and its role in alcohol use disorder.

Authors:  Anushree N Karkhanis; Ream Al-Hasani
Journal:  Brain Res       Date:  2020-02-28       Impact factor: 3.252

6.  Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity.

Authors:  Thomas A Munro; Loren M Berry; Ashlee Van't Veer; Cécile Béguin; F Ivy Carroll; Zhiyang Zhao; William A Carlezon; Bruce M Cohen
Journal:  BMC Pharmacol       Date:  2012-05-29

Review 7.  Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology.

Authors:  Rob Hill; Meritxell Canals
Journal:  Pharmacol Ther       Date:  2021-07-10       Impact factor: 12.310
  7 in total

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