Literature DB >> 2091836

Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety.

S Sonnino1, L Cantu, M Corti, D Acquotti, G Kirschner, G Tettamanti.   

Abstract

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 A and 102 kDa, respectively, down to a concentration of 2.0 x 10(-5) M.

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Year:  1990        PMID: 2091836     DOI: 10.1016/0009-3084(90)90087-8

Source DB:  PubMed          Journal:  Chem Phys Lipids        ISSN: 0009-3084            Impact factor:   3.329


  5 in total

1.  Conformation of the oligosaccharide chain of G(M1) ganglioside in a carbohydrate-enriched surface.

Authors:  P Brocca; P Berthault; S Sonnino
Journal:  Biophys J       Date:  1998-01       Impact factor: 4.033

Review 2.  Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders.

Authors:  Marco Piccinini; Federica Scandroglio; Simona Prioni; Barbara Buccinnà; Nicoletta Loberto; Massimo Aureli; Vanna Chigorno; Elisa Lupino; Giovanni DeMarco; Annarosa Lomartire; Maria Teresa Rinaudo; Sandro Sonnino; Alessandro Prinetti
Journal:  Mol Neurobiol       Date:  2010-02-03       Impact factor: 5.590

3.  LIGA20, a lyso derivative of ganglioside GM1, given orally after cortical thrombosis reduces infarct size and associated cognition deficit.

Authors:  A Kharlamov; I Zivkovic; A Polo; D M Armstrong; E Costa; A Guidotti
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

4.  Metabolism of semisynthetic single-chain GM1 derivatives in cerebellar granule cells in culture.

Authors:  M Pitto; A Miglio; G Kirschner; A Leon; R Ghidoni
Journal:  Neurochem Res       Date:  1991-11       Impact factor: 3.996

5.  Lipids and membrane lateral organization.

Authors:  Sandro Sonnino; Alessandro Prinetti
Journal:  Front Physiol       Date:  2010-11-19       Impact factor: 4.566

  5 in total

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