| Literature DB >> 209163 |
C Huseman, A Johanson, M Varma, R M Blizzard.
Abstract
Three siblings with congenital lipodystrophy were studied extensively for endocrine abnormalities. A severe disturbance in carbohydrate metabolism was observed. Plasma concentrations of glucagon and insulin were markedly elevated both in the basal state and in response to provocative stimuli. In addition, marked resistance to exogenous insulin and a diabetic oral glucose tolerance test were demonstrated. Lipid metabolism, GH, and ACTH secretion were normal...Entities:
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Year: 1978 PMID： 209163 DOI： 10.1016/s0022-3476(78)80500-9
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406