Literature DB >> 2090948

Expression of alpha and beta tubulin genes during the asexual and sexual blood stages of Plasmodium falciparum.

C J Delves1, P Alano, R G Ridley, M Goman, S P Holloway, J E Hyde, J G Scaife.   

Abstract

Malaria parasites switch to sexual development after a period of vegetative growth in the host's erythrocytes. This switch, vital for parasite transmission to mosquitoes, is little understood at the genetic level. Likely candidates for developmental control are the alpha- and beta-tubulin subunits required for microtubule assembly. We report here that the transcription of the alpha- and beta-tubulin genes in Plasmodium falciparum show a radically different pattern of transcription in the sexual and sexual phases of parasite growth. Our studies lead to the conclusion that three transcripts of the beta-tubulin gene differ by sequences in their 5'- or 3'-untranslated regions.

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Year:  1990        PMID： 2090948     DOI： 10.1016/0166-6851(90)90151-b

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  12 in total

Review 1.  Cytoskeleton of apicomplexan parasites.

Authors:  Naomi S Morrissette; L David Sibley
Journal:  Microbiol Mol Biol Rev       Date:  2002-03       Impact factor: 11.056

2.  Defining the morphology and mechanism of the hemoglobin transport pathway in Plasmodium falciparum-infected erythrocytes.

Authors:  Katharine J Milani; Timothy G Schneider; Theodore F Taraschi
Journal:  Eukaryot Cell       Date:  2015-02-27

3.  Cloning and characterization of subunit genes of ribonucleotide reductase, a cell-cycle-regulated enzyme, from Plasmodium falciparum.

Authors:  D Chakrabarti; S M Schuster; R Chakrabarti
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

4.  The gene encoding topoisomerase II from Plasmodium falciparum.

Authors:  S Cheesman; S McAleese; M Goman; D Johnson; P Horrocks; R G Ridley; B J Kilbey
Journal:  Nucleic Acids Res       Date:  1994-07-11       Impact factor: 16.971

5.  Malaria's Eve: evidence of a recent population bottleneck throughout the world populations of Plasmodium falciparum.

Authors:  S M Rich; M C Licht; R R Hudson; F J Ayala
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-14       Impact factor: 11.205

6.  The gene encoding DNA polymerase alpha from Plasmodium falciparum.

Authors:  J H White; B J Kilbey; E de Vries; M Goman; P Alano; S Cheesman; S McAleese; R G Ridley
Journal:  Nucleic Acids Res       Date:  1993-08-11       Impact factor: 16.971

7.  Molecular characterisation and stage-specific expression of proliferating cell nuclear antigen (PCNA) from the malarial parasite, Plasmodium falciparum.

Authors:  B J Kilbey; I Fraser; S McAleese; M Goman; R G Ridley
Journal:  Nucleic Acids Res       Date:  1993-01-25       Impact factor: 16.971

8.  DNA polymerase delta: gene sequences from Plasmodium falciparum indicate that this enzyme is more highly conserved than DNA polymerase alpha.

Authors:  R G Ridley; J H White; S M McAleese; M Goman; P Alano; E de Vries; B J Kilbey
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

9.  The small ribosomal subunit RNA isoforms in Plasmodium cynomolgi.

Authors:  V Corredor; V Enea
Journal:  Genetics       Date:  1994-03       Impact factor: 4.562

10.  Promiscuous expression of α-tubulin II in maturing male and female Plasmodium falciparum gametocytes.

Authors:  Samana Schwank; Colin J Sutherland; Chris J Drakeley
Journal:  PLoS One       Date:  2010-12-30       Impact factor: 3.240
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