Literature DB >> 2090585

Wound tissue respiratory burst and local microbial inflammation.

S M Belotsky1, E V Guzu, V A Karlov, E S Dikovskaya, O B Filjukova, T I Snastina.   

Abstract

Local and systemic chemiluminescent (CL) response was measured in 32 patients with wound infection and in 27 patients with crush syndrome complicated by severe wound infection. The level of wound CL depends upon the local microbial concentration and the dynamics of wound healing. CL response of neutrophils in circulation was higher in higher local CL response, but extremely high wound microbial concentration (greater than 10(8) CFU/g) suppressed both local and systemic responses. No metabolic reserve was observed in wound tissue. Wound healing was characterized by changes in the mode of local CL response: from a prevalence of luminol-dependent (neutrophilic) CL to a prevalence of lucigenin-independent (macrophagal) CL.

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Year:  1990        PMID： 2090585     DOI： 10.1007/BF00916369

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  16 in total

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Authors:  J F BURKE; A A MILES
Journal:  J Pathol Bacteriol       Date:  1958-07

2.  Oxidative response of human neutrophils, monocytes, and alveolar macrophages induced by unopsonized surface-adherent Staphylococcus aureus.

Authors:  M L Devalon; G R Elliott; W E Regelmann
Journal:  Infect Immun       Date:  1987-10       Impact factor: 3.441

3.  Injury to endothelial cells by phagocytosing polymorphonuclear leukocytes and modulatory role of lipoxygenase products.

Authors:  C M Vandenbroucke-Grauls; H M Thijssen; K P van Kessel; B S van Asbeck; J Verhoef
Journal:  Infect Immun       Date:  1987-06       Impact factor: 3.441

4.  Neutrophils adherent to a nonphagocytosable surface (glomerular basement membrane) produce oxidants only at the site of attachment.

Authors:  M C Vissers; W A Day; C C Winterbourn
Journal:  Blood       Date:  1985-07       Impact factor: 22.113

Review 5.  Polymorphonuclear leukocyte-mediated cell and tissue injury: oxygen metabolites and their relations to human disease.

Authors:  J C Fantone; P A Ward
Journal:  Hum Pathol       Date:  1985-10       Impact factor: 3.466

6.  Subcutaneous staphylococcal infection in mice. II. The inflammatory response to different strains of staphylococci and micrococci.

Authors:  D S Agarwal
Journal:  Br J Exp Pathol       Date:  1967-10

7.  The kinetics of peritoneal clearance of Escherichia coli and Bacteroides fragilis and participating defense mechanisms.

Authors:  T Skau; P O Nyström; L Ohman; O Stendahl
Journal:  Arch Surg       Date:  1986-09

8.  Pathogenesis of foreign body infection. Evidence for a local granulocyte defect.

Authors:  W Zimmerli; P D Lew; F A Waldvogel
Journal:  J Clin Invest       Date:  1984-04       Impact factor: 14.808

9.  Neutrophil activity in abscess-bearing mice: comparative studies with neutrophils isolated from peripheral blood, elicited peritoneal exudates, and abscesses.

Authors:  P H Hart; L K Spencer; M F Nulsen; P J McDonald; J J Finlay-Jones
Journal:  Infect Immun       Date:  1986-03       Impact factor: 3.441

10.  Standardized intraabdominal abscess formation with generalized sepsis: pathophysiology in the rat.

Authors:  L Hansson; A Alwmark; P Christensen; B Jeppsson; E Holst; S Bengmark
Journal:  Eur Surg Res       Date:  1985       Impact factor: 1.745
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  1 in total

Review 1.  The structure-function relationship of Pseudomonas aeruginosa in infections and its influence on the microenvironment.

Authors:  Mads Lichtenberg; Tim Holm Jakobsen; Michael Kühl; Mette Kolpen; Peter Østrup Jensen; Thomas Bjarnsholt
Journal:  FEMS Microbiol Rev       Date:  2022-09-02       Impact factor: 15.177
  1 in total

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