Literature DB >> 2090150

Lectins: mediators of adhesion for bacteria in infectious diseases and for tumor cells in metastasis.

J Beuth1, H L Ko, W Roszkowski, K Roszkowski, Y Ohshima.   

Abstract

Adhesion of bacteria and adhesion of tumor cells have much in common, especially the participation of lectins in this process. In the future it might be possible to inhibit the metastatic process into the liver (e.g. during surgical operations of malignant tumors) and bacterial adherence to mucosal linings or plastic devices by blocking of adhesion molecules (lectins) with appropriate glycoconjugates. Initial clinical trials are very promising.

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Year:  1990        PMID: 2090150     DOI: 10.1016/s0934-8840(11)80692-4

Source DB:  PubMed          Journal:  Zentralbl Bakteriol        ISSN: 0934-8840


  2 in total

1.  Hepatocellular injury inhibits lectin-mediated tumor colonization into BALB/c-mice livers.

Authors:  J Beuth; H L Ko; M Steuer; G Pulverer
Journal:  Experientia       Date:  1993-07-05

2.  Cytotoxicity of Pseudomonas aeruginosa internal lectin PA-I to respiratory epithelial cells in primary culture.

Authors:  O Bajolet-Laudinat; S Girod-de Bentzmann; J M Tournier; C Madoulet; M C Plotkowski; C Chippaux; E Puchelle
Journal:  Infect Immun       Date:  1994-10       Impact factor: 3.441

  2 in total

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