Literature DB >> 2090101

Alterations in the heart lysosomal stability in isoproterenol induced myocardial infarction in rats.

L V Ravichandran1, R Puvanakrishnan, K T Joseph.   

Abstract

The alterations in the heart lysosomal stability following isoproterenol induced myocardial infarction were studied in albino rats. The rate of release of beta-glucuronidase at various time intervals at 37 degrees C from lysosome rich fraction was taken as a measure of lysosomal stability. As compared to the control day one, three and five samples exhibited a significant increase in beta-glucuronidase activity at all the time intervals. The subcellular distribution of beta-glucuronidase was also studied and the soluble and total activities exhibited an increase at peak infarction stage and returned to normal during the recovery. The decrease in the lysosomal stability might be attributed to the increased beta-glucuronidase activity observed following myocardial infarction.

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Year:  1990        PMID： 2090101

Source DB:  PubMed          Journal:  Biochem Int        ISSN： 0158-5231


  9 in total

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2.  Morin protects heart from beta-adrenergic-stimulated myocardial infarction: an electrocardiographic, biochemical, and histological study in rats.

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Journal:  Mol Cell Biochem       Date:  2002-01       Impact factor: 3.396

4.  Antilipoperoxidative and membrane stabilizing effect of diosgenin, in experimentally induced myocardial infarction.

Authors:  K S Jayachandran; Hannah R Vasanthi; G V Rajamanickam
Journal:  Mol Cell Biochem       Date:  2009-02-21       Impact factor: 3.396

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Journal:  Cell Stress Chaperones       Date:  2009-03-18       Impact factor: 3.667

Review 6.  Complementary and alternative medicine use in rheumatoid arthritis: proposed mechanism of action and efficacy of commonly used modalities.

Authors:  Petros Efthimiou; Manil Kukar
Journal:  Rheumatol Int       Date:  2009-10-30       Impact factor: 2.631

7.  Effect of nicorandil and amlodipine on bio-chemical parameters during isoproterenol induced myocardial necrosis in rats.

Authors:  Narinder Singh; Rahat Kumar
Journal:  Indian J Clin Biochem       Date:  2003-01

8.  Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline via PPARγ activation in diabetic rats.

Authors:  Mohammad Badavi; Seyyed Ali Mard; Mahin Dianat; Neda Dashtbozorgi
Journal:  J Diabetes Metab Disord       Date:  2020-11-18

9.  A novel tetrapeptide derivative exhibits in vitro inhibition of neutrophil-derived reactive oxygen species and lysosomal enzymes release.

Authors:  Sumitra Miriyala; Manikandan Panchatcharam; Meera Ramanujam; Rengarajulu Puvanakrishnan
Journal:  Oxid Med Cell Longev       Date:  2013-05-30       Impact factor: 6.543
  9 in total

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