| Literature DB >> 208964 |
H Ishikawa, M Shino, E G Rennels.
Abstract
We recently established a clone (2B8) of normal rat prolactin cells that secretes only prolactin into the medium. When grown in the presence of thyrotrophin-releasing hormone (TRH), estradiol (E2) or arginine vasotocin (AVT), the cells show increased production of prolactin. Subclones of single cell origin were developed from 2B8 cells exposed for 1 week to TRH, E2 or TRH plus E2. These subclones differ in their response to TRH, E2 or AVT and therefore may possess different receptors for these hormones.Entities:
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Year: 1978 PMID： 208964 DOI： 10.1007/bf02617921
Source DB: PubMed Journal: In Vitro ISSN： 0073-5655