| Literature DB >> 2089354 |
C Eckardt1, D Schmidt, M Czank.
Abstract
Different methylphenylsilicone (MPS) and fluorosilicone (FS) oils having a higher specific gravity than water were investigated as vitreous replacements. Their intraocular tolerance in vitrectomized aphakic rabbit eyes was evaluated for periods of up to 4 months and compared to that of regular polydimethylsilicone oil (PDMS). Weakly fluorinated FS and weakly phenylated MPS showed a presumably toxic effect on the retina. As compared to highly fluorinated FS, highly phenylated MPS showed better intraocular tolerance; however, inflammatory reaction was slightly more extensive than in eyes filled with PDMS.Entities:
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Year: 1990 PMID: 2089354 DOI: 10.1159/000310141
Source DB: PubMed Journal: Ophthalmologica ISSN: 0030-3755 Impact factor: 3.250