Literature DB >> 2089109

The synaptic noradrenaline concentration in humans as estimated from simultaneous measurements of plasma noradrenaline and dihydroxyphenylglycol (DOPEG).

J Ludwig1, M Gerlich, T Halbrügge, K H Graefe.   

Abstract

A linear relationship between plasma DOPEG (ordinate) and plasma noradrenaline (NA; abscissa) was found during orthostasis as well as during NA infusion. The slope of the former (slopeR) was 13 times steeper than that of the latter (slopeI). This difference in slopes suggests that the NA concentration in the synaptic cleft is markedly higher than in plasma. The factor (F) characterizing this concentration difference was obtained from F2 = slopeR/slopeI. It amounted to 3.6.

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Year:  1990        PMID： 2089109     DOI： 10.1007/978-3-7091-9113-2_60

Source DB:  PubMed          Journal:  J Neural Transm Suppl        ISSN： 0303-6995


  4 in total

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3.  Estimation of noradrenaline concentrations in the axoplasm of noradrenergic neurones in man.

Authors:  J Ludwig; T Halbrügge; M Gerlich; K H Graefe
Journal:  Clin Auton Res       Date:  1992-06       Impact factor: 4.435

4.  Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells.

Authors:  Alexander Hamilton; Quan Zhang; Albert Salehi; Mara Willems; Jakob G Knudsen; Anna K Ringgaard; Caroline E Chapman; Alejandro Gonzalez-Alvarez; Nicoletta C Surdo; Manuela Zaccolo; Davide Basco; Paul R V Johnson; Reshma Ramracheya; Guy A Rutter; Antony Galione; Patrik Rorsman; Andrei I Tarasov
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  4 in total

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