Literature DB >> 20890939

Assessment of benefits of a universal screen for maternal alcohol use during pregnancy.

Anne E Gifford1, Kathleen J Farkas, Leila W Jackson, Christopher D Molteno, Joseph L Jacobson, Sandra W Jacobson, Cynthia F Bearer.   

Abstract

INTRODUCTION: The objective of this report is to estimate the benefits of universal meconium screening for maternal drinking during pregnancy. Fetal alcohol spectrum disorder (FASD), including its most severe manifestation fetal alcohol syndrome (FAS), is preventable and remains a public health tragedy. The incidences of FAS and FASD have been conservatively estimated to be 0.97 and 10 per 1000 births, respectively. Meconium testing has been demonstrated to be a promising at-birth method for detection of drinking during pregnancy.
METHODS: The current costs of FAS and FASD, alcohol treatment programs, and meconium screening were estimated by literature review. Monetary values were converted roughly to equal dollars in 2006.
RESULTS: Costs of adding meconium analysis to the current newborn screening program and of treatment for the identified mothers were estimated and compared to potential averted costs that may result from identification and intervention for mothers and affected infants. Three potential maternal treatment strategies are analyzed. Depending on the treatment type, the savings may range from $6 to $97 for every $1 spent on screening and treatment. DISCUSSION: It needs to be emphasized, however, that such screening is premature and that to be effective this screening can be implemented only if there is a societal willingness to institute prevention and intervention programs to improve both women's and children's health. Future research should be directed at improving detection and developing in-depth prevention and remedial intervention programs. A thorough consideration of the ethical issues involved in such a screening program is also needed.
© 2010 Wiley-Liss, Inc.

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Year:  2010        PMID: 20890939      PMCID: PMC3733546          DOI: 10.1002/bdra.20731

Source DB:  PubMed          Journal:  Birth Defects Res A Clin Mol Teratol        ISSN: 1542-0752


  36 in total

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Review 4.  Incidence of fetal alcohol syndrome and prevalence of alcohol-related neurodevelopmental disorder.

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8.  Universal or targeted screening for fetal alcohol exposure: a cost-effectiveness analysis.

Authors:  Robert B Hopkins; Jon Paradis; Tozheg Roshankar; James Bowen; Jean-Eric Tarride; Gord Blackhouse; Morgan Lim; Daria O'Reilly; Ron Goeree; Christopher J Longo
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Review 9.  An update on incidence of FAS: FAS is not an equal opportunity birth defect.

Authors:  E L Abel
Journal:  Neurotoxicol Teratol       Date:  1995 Jul-Aug       Impact factor: 3.763

10.  Programme costs in the economic evaluation of health interventions.

Authors:  Benjamin Johns; Rob Baltussen; Raymond Hutubessy
Journal:  Cost Eff Resour Alloc       Date:  2003-02-26
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3.  Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule.

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4.  The feasibility and cost of neonatal screening for prenatal alcohol exposure by measuring phosphatidylethanol in dried blood spots.

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6.  Meconium indicators of maternal alcohol abuse during pregnancy and association with patient characteristics.

Authors:  Tamme W Goecke; Pascal Burger; Peter A Fasching; Abdulsallam Bakdash; Anne Engel; Lothar Häberle; Franziska Voigt; Florian Faschingbauer; Eva Raabe; Nicolai Maass; Michael Rothe; Matthias W Beckmann; Fritz Pragst; Johannes Kornhuber
Journal:  Biomed Res Int       Date:  2014-03-30       Impact factor: 3.411

Review 7.  Fetal alcohol-spectrum disorders: identifying at-risk mothers.

Authors:  Annika C Montag
Journal:  Int J Womens Health       Date:  2016-07-21
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