Literature DB >> 20890001

Localisation of occult breast lesion: a comparative analysis of hookwire and radioguided procedures.

Tiffany Y C Chu1, C Y Lui, W K Hung, S K Kei, Catherine L Y Choi, H S Lam.   

Abstract

OBJECTIVES: For occult breast lesions, to retrospectively compare the performance of radioguided and hookwire methods in terms of ease of localisation and surgical procedures, and the ability to obtain a specimen with a clear margin.
DESIGN: Retrospective study.
SETTING: Regional hospital, Hong Kong. PATIENTS: All patients who underwent occult breast lesion localisation by either ultrasonography- or stereotactic-guided radioguided occult lesion localisation or hookwire localisation from August 2003 to December 2007 were included. MAIN OUTCOME MEASURES: Demographic data, localisation and operation procedure time, size of specimens and margin clearance.
RESULTS: In all, 165 patients (mean age, 52 years) having these procedures were assessed. In 98 instances, the procedure (hookwire=53, radioguided=45) was for diagnostic purposes and in 67 (hookwire=23, radioguided=44) for therapy. Both techniques attained a very high success rate (>95%). For radioguided occult lesion localisation, there was a significantly shorter mean localisation time than for hookwire localisation (18 min versus 31 min; P<0.001), while the mean operating time was similar. Radioguided occult lesion localisation entailed larger specimens and fewer cases with close or involved margins, or recourse to intra-operative re-excision or a second operation, but these differences were not statistically significant. Within the radioguided occult lesion localisation group, there were 42 patients who had a simultaneous sentinel lymph node biopsy (sentinel node and occult lesion localisation), with a 98% success rate although no lymph node metastasis was revealed.
CONCLUSION: Radioguided occult lesion localisation excels in yielding a much shorter localisation time and is as good as hookwire localisation in terms of specimen margin clearance and need for re-excision. It also offers the advantage of enabling simultaneous sentinel lymph node biopsy for invasive cancers. Therefore it is a recommended procedure that should be used more widely.

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Year:  2010        PMID: 20890001

Source DB:  PubMed          Journal:  Hong Kong Med J        ISSN: 1024-2708            Impact factor:   2.227


  4 in total

1.  Isotope-guided surgery for nonpalpable breast cancer.

Authors:  Man Po Chow; Wai Ka Hung; Tiffany Chu; Chun Ying Lui; Marcus Ying; Kong Ling Mak; Miranda Chan
Journal:  World J Surg       Date:  2011-01       Impact factor: 3.352

2.  Incidence and risk factors of the intraoperative localization failure of nonpalpable breast lesions by radio-guided occult lesion localization: a retrospective analysis of 579 cases.

Authors:  Sergio Bernardi; Serena Bertozzi; Ambrogio P Londero; Giuliana Gentile; Francesco Giacomuzzi; Arnalda Carbone
Journal:  World J Surg       Date:  2012-08       Impact factor: 3.352

3.  Radioguided localisation of impalpable breast lesions using 99m-Technetium macroaggregated albumin: Lessons learnt during introduction of a new technique to guide preoperative localisation.

Authors:  Joanne Landman; Sagarika Kulawansa; Michael McCarthy; Russell Troedson; Michael Phillips; Jill Tinning; Donna Taylor
Journal:  J Med Radiat Sci       Date:  2013-12-25

4.  Assessment of Ultrasound / Radio-guided Occult Lesion Localization in Non-palpable Breast Lesions.

Authors:  Seyed Ali Alamdaran; Donia Farokh; Ayda Sharifi Haddad; Navid Daghighi; Elaheh Modoodi; Ramin Sadeghi; Mohammad Naser Forghani; Asieh Sadat Fattahi
Journal:  Asia Ocean J Nucl Med Biol       Date:  2018
  4 in total

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