Literature DB >> 20887522

Management of third molar removal with a single dose of recombinant Factor IX (BeneFIX) and local measures in severe haemophilia B.

I D Hewson1, P Makhmaloaf.   

Abstract

BACKGROUND: Patients with inherited bleeding disorders have historically had factor cover for oral surgery. Factor support is expensive, time consuming and places the patient at a potential risk of blood-borne diseases. This case describes the use of a significant reduction in factor support for a severe haemophilia B patient having third molars surgically removed.
METHODS: Local measures were used after a single preoperative dose of Factor IX to obtain good postoperative haemostasis.
RESULTS: Excellent haemostasis was achieved using local measures of 5% tranexamic acid solution, Surgicel® and Monocryl® sutures after a single preoperative dose of Factor IX.
CONCLUSIONS: Oral surgery may be performed on patients with inherited bleeding disorders using minimal factors and local haemostatic measures. A study of this patient population has commenced at The Alfred Hospital.

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Year:  2010        PMID: 20887522     DOI: 10.1111/j.1834-7819.2010.01242.x

Source DB:  PubMed          Journal:  Aust Dent J        ISSN: 0045-0421            Impact factor:   2.291


  3 in total

1.  Infected tooth extraction, bone grafting, immediate implant placement and immediate temporary crown insertion in a patient with severe type-B hemophilia.

Authors:  Jose Luis Calvo-Guirado; Georgios E Romanos; Rafael Arcesio Delgado-Ruiz
Journal:  BMJ Case Rep       Date:  2019-03-22

2.  No increased bleeding risk for oral surgery in patients with severe congenital bleeding disorders due to intense perioperative management.

Authors:  G Goldmann; C Berens; N Marquardt; R Reich; J Oldenburg; M Wenghoefer
Journal:  Oral Maxillofac Surg       Date:  2014-12-10

3.  Management of dental extraction in patients with Haemophilia A and B: a report of 58 extractions.

Authors:  Andre Peisker; Gregor-Franziskus Raschke; Stefan Schultze-Mosgau
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2014-01-01
  3 in total

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