Literature DB >> 20882897

Malignant mixed mullerian tumor of the cervix including components of a rhabdomyosarcoma: case report and literature review.

S H Lee1, J Kim, J H Kim, K H Lee, J S Park, S Y Hur.   

Abstract

Malignant mixed mesodermal tumors (MMMTs) are composed of carcinomatous and sarcomatous components and have an aggressive metastatic potential, resulting in a poor prognosis. MMMTs of gynecologic origin typically arise from either the ovary or the uterus, and MMMTs of the cervix are extremely rare. Due to the rarity of MMMTs arising from the cervix, there is no consensus regarding treatment, prognosis, and outcome; however, aggressive surgical cytoreduction, combined with adjuvant platinum-based chemotherapy and/or radiotherapy, is recommended as the treatment of choice for MMMTs of the cervix. Cervical MMMTs are more often confined to the uterus at the time of diagnosis and frequently have non-glandular epithelial components. For these reasons, MMMTs of the cervix may have a better prognosis compared to the uterine counterparts. A case of an immunohistochemically confirmed primary MMMT of the cervix, including components of a rhabdomyosarcoma, is reported.

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Year:  2010        PMID: 20882897

Source DB:  PubMed          Journal:  Eur J Gynaecol Oncol        ISSN: 0392-2936            Impact factor:   0.196


  3 in total

1.  Multiple pulmonary metastases with halo-sign from malignant mixed Müllerian tumors.

Authors:  Hong-Wei Tian; Wei-Bing Yang; Meng-Jie Yang; Jing-Yuan Liu; Jian-Chu Zhang; Xiao-Nan Tao; Qiong Zhou
Journal:  Oncol Lett       Date:  2017-09-22       Impact factor: 2.967

Review 2.  Cervical Carcinosarcoma: Current Understanding on Pathogenesis, Diagnosis, Management and Future Perspectives.

Authors:  Xinyao Shu; Yuwen Zhou; Guixia Wei; Xiaorong Chen; Meng Qiu
Journal:  Clin Med Insights Oncol       Date:  2021-12-08

3.  Malignant müllerian mixed tumor of the uterine cervix with a small cell neuroendocrine carcinoma component.

Authors:  Satoru Munakata; Emi Iwai; Tomohito Tanaka; Michihiko Nakamura; Takayoshi Kanda
Journal:  Case Rep Pathol       Date:  2013-02-26
  3 in total

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