Literature DB >> 20882432

Case of TTP with cerebral infarct secondary to platelet transfusion.

Sushil P Tripathi1, Anand S Deshpande, Sandhya Khadse, Rajesh K Kulkarni.   

Abstract

BACKGROUND: Thrombotic thrombocytopenic purpura (TTP) is a rare disease in children with significant mortality in cases who do not receive appropriate treatment. CASE: The author describe a 3-year-old child who presented with skin bleeds, microangiopathic anemia, thrombocytopenia and right sided hemi paresis with aphasia and altered sensorium following platelet transfusion.
CONCLUSION: A diagnosis of thrombotic thrombocytopenic purpura was made and the child recovered dramatically after giving fresh frozen plasma and steroids.

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Year:  2010        PMID: 20882432     DOI: 10.1007/s12098-010-0224-9

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  7 in total

Review 1.  Current understanding of the pathophysiology of thrombotic thrombocytopenic purpura.

Authors:  S L Allford; S J Machin
Journal:  J Clin Pathol       Date:  2000-07       Impact factor: 3.411

Review 2.  Plasmapheresis in thrombotic microangiopathy-associated syndromes: review of outcome data derived from clinical trials and open studies.

Authors:  Hans von Baeyer
Journal:  Ther Apher       Date:  2002-08

Review 3.  Thrombotic thrombocytopenic purpura: a treatable cause of childhood encephalopathy.

Authors:  E R Lawlor; D W Webb; A Hill; L D Wadsworth
Journal:  J Pediatr       Date:  1997-02       Impact factor: 4.406

4.  Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group.

Authors:  G A Rock; K H Shumak; N A Buskard; V S Blanchette; J G Kelton; R C Nair; R A Spasoff
Journal:  N Engl J Med       Date:  1991-08-08       Impact factor: 91.245

5.  Hazard of platelet transfusion in thrombotic thrombocytopenic purpura.

Authors:  D R Harkness; J J Byrnes; E C Lian; W D Williams; G T Hensley
Journal:  JAMA       Date:  1981 Oct 23-30       Impact factor: 56.272

6.  Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion.

Authors:  H M Tsai
Journal:  Blood       Date:  1996-05-15       Impact factor: 22.113

Review 7.  Thrombotic thrombocytopenic purpura in childhood.

Authors:  Maria C Bouw; Natasja Dors; Heleen van Ommen; Nicole L Ramakers-van Woerden
Journal:  Pediatr Blood Cancer       Date:  2009-10       Impact factor: 3.167

  7 in total
  2 in total

1.  Acquired thrombotic thrombocytopenic purpura in children: a single institution experience.

Authors:  Somasundaram Jayabose; Theodore S Nowicki; Julie Dunbar; Oya Levendoglu-Tugal; Mehmet F Ozkaynak; Claudio Sandoval
Journal:  Indian J Pediatr       Date:  2012-12-21       Impact factor: 1.967

2.  Prognostic risk-stratified score for predicting mortality in hospitalized patients with thrombotic thrombocytopenic purpura: nationally representative data from 2007 to 2012.

Authors:  Ruchika Goel; Karen E King; Clifford M Takemoto; Paul M Ness; Aaron A R Tobian
Journal:  Transfusion       Date:  2016-04-15       Impact factor: 3.157

  2 in total

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